F
Fergus Shanahan
Researcher at National University of Ireland
Publications - 727
Citations - 59181
Fergus Shanahan is an academic researcher from National University of Ireland. The author has contributed to research in topics: Inflammatory bowel disease & Gut flora. The author has an hindex of 117, co-authored 705 publications receiving 51963 citations. Previous affiliations of Fergus Shanahan include Imperial College London & Mater Misericordiae Hospital.
Papers
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Journal ArticleDOI
Differentiation-associated expression of the Epstein-Barr virus BZLF1 transactivator protein in oral hairy leukoplakia.
Lawrence S. Young,R. Lau,Martin Rowe,Gerald Niedobitek,Graham Packham,Fergus Shanahan,D T Rowe,Deborah Greenspan,John S. Greenspan,Alan B. Rickinson +9 more
TL;DR: A monoclonal antibody to BZLF1 is generated which reacts in immunohistology, immunoblotting, and immunoprecipitation and which recognizes both the active, dimeric form and the inactive, monomeric form of the protein.
Journal ArticleDOI
Bifidobacterium infantis 35624 administration induces Foxp3 T regulatory cells in human peripheral blood: potential role for myeloid and plasmacytoid dendritic cells.
Patrycja Konieczna,David Groeger,Mario Ziegler,Remo Frei,Ruth Ferstl,Fergus Shanahan,Eamonn Martin Quigley,Barry Kiely,Cezmi A. Akdis,Liam O'Mahony +9 more
TL;DR: B infantis administration to humans selectively promotes immunoregulatory responses, suggesting that this microbe may have therapeutic utility in patients with inflammatory disease.
BookDOI
Inflammatory Bowel Disease: From Bench to Bedside
TL;DR: This chapter discusses the development of novel mouse models of Inflammatory Bowel Disease, and the role of the Microcirculation in Chronic Gut Inflammation and 'Disease Management' in Chronic Medical Conditions.
Journal ArticleDOI
Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis.
Pauline D. Scanlan,Fergus Shanahan,Yvonne Clune,John Kevin Collins,Gerald C. O'Sullivan,Micheal O'Riordan,Elaine Holmes,Yulan Wang,Julian R. Marchesi +8 more
TL;DR: The intestinal microbiota and their metabolites are significantly altered in both colorectal cancer and polypectomized subjects compared with controls, and a clear division in the metabonome was observed.
Journal ArticleDOI
A molecular analysis of fecal and mucosal bacterial communities in irritable bowel syndrome
Caroline E. Codling,Caroline E. Codling,Liam O'Mahony,Fergus Shanahan,Eamonn Martin Quigley,Julian R. Marchesi,Julian R. Marchesi,Julian R. Marchesi +7 more
TL;DR: IBS impacts equally on both bacterial communities in the IBS host and a significant difference in the gut microbiota exists between fecal samples from IBS patients and healthy controls, which is unclear and various possible explanations are available.