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Fergus Shanahan

Researcher at National University of Ireland

Publications -  727
Citations -  59181

Fergus Shanahan is an academic researcher from National University of Ireland. The author has contributed to research in topics: Inflammatory bowel disease & Gut flora. The author has an hindex of 117, co-authored 705 publications receiving 51963 citations. Previous affiliations of Fergus Shanahan include Imperial College London & Mater Misericordiae Hospital.

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Regulation of CEACAM Family Members by IBD-Associated Triggers in Intestinal Epithelial Cells, Their Correlation to Inflammation and Relevance to IBD Pathogenesis

TL;DR: In this paper, the authors investigated the role of CEACAMs in the onset and pathogenesis of IBD in patients suffering from colon cancer and inflammatory bowel diseases (IBD), and they found that CEAM1, -3, -5, -6, -7 expression correlated with the degree of inflammation in pediatric and adult IBD colon biopsies.
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A randomised, double-blind, placebo-controlled clinical study: the effects of a synbiotic, Lepicol, in adults with chronic, functional constipation.

TL;DR: Symptoms of constipation improved to a greater degree and there was a significant reduction in laxative use in the Lepicol group, and both groups showed significant improvements in quality of life scores at 4 weeks.
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Separating the microbiome from the hyperbolome.

TL;DR: The microbiome is moving quickly towards the clinic, with successes including fecal microbial transplants for recurring Clostridium difficile, hints of new antibiotics to come, and possible new microbial biomarkers for common complex diseases.