F
Fergus Shanahan
Researcher at National University of Ireland
Publications - 727
Citations - 59181
Fergus Shanahan is an academic researcher from National University of Ireland. The author has contributed to research in topics: Inflammatory bowel disease & Gut flora. The author has an hindex of 117, co-authored 705 publications receiving 51963 citations. Previous affiliations of Fergus Shanahan include Imperial College London & Mater Misericordiae Hospital.
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Journal ArticleDOI
Altered levels of biochemical indices of bone turnover and bone-related vitamins in patients with Crohn's disease and ulcerative colitis
TL;DR: This work has shown that the pathogenesis of inflammatory bowel disease‐associated osteopenia may be related to pathological rates of bone turnover, and the literature shows mixed results.
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A Randomised Controlled Trial of a Probiotic Lactobacillus Strain in Healthy Adults: Assessment of its Delivery, Transit and Influence on Microbial Flora and Enteric Immunity
Kevin Collins,Colum P. Dunne,Lisa Murphy,Darrin Morrissey,Liam O'Mahony,E. O'Sullivan,Gerald F. Fitzgerald,Barry Kiely,Gerald C. O'Sullivan,Charles Daly,Philippe Marteau,Fergus Shanahan +11 more
TL;DR: Lactobacillus UCC118 was found to effectively transit (and persist within) the human intestinal tract, to modify the faecal flora and to engage the immune system.
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Hidradenitis Suppurativa: Glucose Tolerance, Clinical, Microbiologic, and Immunologic Features and HLA Frequencies in 27 Patients
TL;DR: It is suggested that T lymphocytes may play a role in the pathogenesis of hidradenitis suppurativa and that HLA-A1 andHLA-B8 may predispose the patient to more severe disease, but further research is necessary to clarify this.
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Identification of a Unique Hybrid Macrophage-Polarization State following Recovery from Lipopolysaccharide Tolerance
TL;DR: Recovery from LPS tolerance leads to a hybrid macrophage activation state that is proinflammatory and microbicidal in nature but that possesses a regulatory anti-inflammatory profile distinct from that of L PS-tolerant and LPS-activated macrophages.
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Diagnostic Accuracy of Computed Tomography Using Lower Doses of Radiation for Patients With Crohn's Disease
Orla F. Craig,Siobhan B. O’Neill,Fiona O’Neill,Patrick D. McLaughlin,AnneMarie McGarrigle,Sebastian McWilliams,Owen J. O'Connor,Alan N. Desmond,Elizabeth Kenny Walsh,Max F. Ryan,Michael M. Maher,Fergus Shanahan +11 more
TL;DR: Although low-dose CT images are of lower quality than images obtained with conventional doses of radiation, no clinically significant diagnostic findings were missed from low- dose CT images of patients with Crohn's disease.