F
Fergus Shanahan
Researcher at National University of Ireland
Publications - 727
Citations - 59181
Fergus Shanahan is an academic researcher from National University of Ireland. The author has contributed to research in topics: Inflammatory bowel disease & Gut flora. The author has an hindex of 117, co-authored 705 publications receiving 51963 citations. Previous affiliations of Fergus Shanahan include Imperial College London & Mater Misericordiae Hospital.
Papers
More filters
Journal ArticleDOI
Exercise and associated dietary extremes impact on gut microbial diversity
Siobhan F. Clarke,Siobhan F. Clarke,Eileen F. Murphy,Orla O'Sullivan,Alice J. Lucey,Margaret Humphreys,Aileen Hogan,Paula A. Hayes,O'Reilly M,Ian B. Jeffery,Ruth Wood-Martin,David M. Kerins,Eamonn Martin Quigley,R. Paul Ross,R. Paul Ross,Paul W. O'Toole,Michael G. Molloy,Eanna Falvey,Fergus Shanahan,Paul D. Cotter,Paul D. Cotter +20 more
TL;DR: Evidence is provided for a beneficial impact of exercise on gut microbiota diversity but also indicate that the relationship is complex and is related to accompanying dietary extremes.
Journal ArticleDOI
The fas counterattack : fas-mediated T cell killing by colon cancer cells expressing fas ligand
TL;DR: A Fas counterattack model for immune escape in colon cancer is suggested, whereby the cancer cells resist Fas-mediated T cell cytotoxicity but express functional FasL, an apoptotic death signal to which activated T cells are inherently sensitive.
Journal ArticleDOI
In vitro selection criteria for probiotic bacteria of human origin: correlation with in vivo findings
Colum P. Dunne,Liam O'Mahony,Lisa Murphy,Gerardine Mary Thornton,Darrin Morrissey,Sile O'Halloran,Maria Feeney,Sarah Flynn,Gerald F. Fitzgerald,Charles Daly,Barry Kiely,Gerald C. O'Sullivan,Fergus Shanahan,John Kevin Collins +13 more
TL;DR: Criteria for in vitro selection of probiotic bacteria that may reflect certain in vivo effects on the host such as modulation of gastrointestinal tract microflora is developed.
Journal ArticleDOI
Composition and energy harvesting capacity of the gut microbiota: relationship to diet, obesity and time in mouse models
Eileen F. Murphy,Paul D. Cotter,Paul D. Cotter,Selena Healy,Tatiana M. Marques,Tatiana M. Marques,Orla O'Sullivan,Orla O'Sullivan,Fiona Fouhy,Siobhan F. Clarke,Siobhan F. Clarke,Paul W. O'Toole,Eamonn Martin Quigley,Catherine Stanton,Catherine Stanton,Paul Ross,Paul Ross,Robert M. O'Doherty,Robert M. O'Doherty,Fergus Shanahan +19 more
TL;DR: The relationship between the microbial composition and energy harvesting capacity is more complex than previously considered and the possibility of microbial adaptation to diet and time should be considered in future studies.
Journal ArticleDOI
Efficacy of an encapsulated probiotic Bifidobacterium infantis 35624 in women with irritable bowel syndrome.
Peter J. Whorwell,Linda Altringer,Jorge G. Morel,Yvonne Bond,Duane Larry Charbonneau,Liam O'Mahony,Barry Kiely,Fergus Shanahan,Eamonn Martin Quigley +8 more
TL;DR: B. infantis 35624 at a dose of 1 × 108 cfu was significantly superior to placebo and all other bifidobacterium doses for the primary efficacy variable of abdominal pain as well as the composite score and scores for bloating, bowel dysfunction, incomplete evacuation, straining, and the passage of gas at the end of the 4-wk study.