F
Fergus Shanahan
Researcher at National University of Ireland
Publications - 727
Citations - 59181
Fergus Shanahan is an academic researcher from National University of Ireland. The author has contributed to research in topics: Inflammatory bowel disease & Gut flora. The author has an hindex of 117, co-authored 705 publications receiving 51963 citations. Previous affiliations of Fergus Shanahan include Imperial College London & Mater Misericordiae Hospital.
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Journal ArticleDOI
Comparative aspects of mast cell heterogeneity in different species and sites.
John Bienenstock,Dean Befus,Judah A. Denburg,Toshihiro Goto,Timothy D.G. Lee,Hirokuni Otsuka,Fergus Shanahan +6 more
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Tissue viral load variability in chronic hepatitis C.
Liam J. Fanning,Joseph Loane,Elizabeth Kenny-Walsh,Margaret Sheehan,Michael Whelton,William O. Kirwan,John Kevin Collins,Fergus Shanahan +7 more
TL;DR: Hepatic viral load variability does not suffer from the same degree of heterogeneity of sampling variability as does histology, and is concordant with serum positivity in all cases.
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Bifidobacterium animalis AHC7 protects against pathogen-induced NF-κB activation in vivo
David O'Mahony,Sharon Murphy,Thomas W.-M. Boileau,JeanSoon Park,Frances O'Brien,David Groeger,Patrycja Konieczna,Mario Ziegler,Paul Scully,Fergus Shanahan,Barry Kiely,Liam O'Mahony +11 more
TL;DR: The cellular mechanism underpinning Bifidobacterium animalis AHC7 mediated attenuation of NF-κB activation may include recognition of the bacterium by dendritic cells and induction of CD25+Foxp3+ T cells.
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Bifidobacterium breve with α-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome.
Eoin Barrett,Eoin Barrett,Patrick Fitzgerald,Timothy G. Dinan,John F. Cryan,R. Paul Ross,R. Paul Ross,Eamonn Martin Quigley,Fergus Shanahan,Barry Kiely,Gerald F. Fitzgerald,Paul W. O'Toole,Catherine Stanton,Catherine Stanton +13 more
TL;DR: The aim of this study was to compare the impact of dietary supplementation with a Bifidobacterium breve strain together with linoleic acid & α-linolenic acid, for 7 weeks, on colonic sensitivity and fatty acid metabolism in rats.
Journal ArticleDOI
Human mucosal T-cell cytotoxicity
TL;DR: The profile of target cell susceptibility and the inhibitory effects of anti-CD45 antibody suggest that the CD45 molecule on the effector cell may be an important determinant ofAnti-CD3-T sensitivity, which might have important implications in inflammatory bowel disease, where the antigen(s) inciting the mucosal immune reactivity is not certain.