F
Frank Rügheimer
Researcher at Pasteur Institute
Publications - 13
Citations - 1116
Frank Rügheimer is an academic researcher from Pasteur Institute. The author has contributed to research in topics: Graphical model & Bayesian network. The author has an hindex of 5, co-authored 13 publications receiving 991 citations. Previous affiliations of Frank Rügheimer include Columbia University & Otto-von-Guericke University Magdeburg.
Papers
More filters
Journal ArticleDOI
Condition-Dependent Transcriptome Reveals High-Level Regulatory Architecture in Bacillus subtilis
Pierre Nicolas,Ulrike Mäder,Etienne Dervyn,Tatiana Rochat,Aurélie Leduc,Nathalie Pigeonneau,Elena Bidnenko,Elodie Marchadier,Mark Hoebeke,Stéphane Aymerich,Dörte Becher,Paola Bisicchia,Eric Botella,Olivier Delumeau,Geoff Doherty,Emma L. Denham,Mark J. Fogg,Vincent Fromion,Anne Goelzer,Annette Hansen,Elisabeth Härtig,Colin R. Harwood,Georg Homuth,Hanne Østergaard Jarmer,Matthieu Jules,Edda Klipp,Ludovic Le Chat,François Lecointe,Peter J. Lewis,Wolfram Liebermeister,Anika March,Ruben A. T. Mars,Priyanka Nannapaneni,David Noone,Susanne Pohl,Bernd Rinn,Frank Rügheimer,Praveen K. Sappa,Franck Samson,Marc Schaffer,Benno Schwikowski,Leif Steil,Jörg Stülke,Thomas Wiegert,Kevin M. Devine,Anthony J. Wilkinson,Jan Maarten van Dijl,Michael Hecker,Uwe Völker,Philippe Bessières,Philippe Noirot +50 more
TL;DR: The transcriptomes of Bacillus subtilis exposed to a wide range of environmental and nutritional conditions that the organism might encounter in nature are reported, offering an initial understanding of why certain regulatory strategies may be favored during evolution of dynamic control systems.
Journal ArticleDOI
Global Network Reorganization During Dynamic Adaptations of Bacillus subtilis Metabolism
Joerg Martin Buescher,Wolfram Liebermeister,Matthieu Jules,Markus Uhr,Jan Muntel,Eric Botella,Bernd Hessling,Roelco J. Kleijn,Ludovic Le Chat,François Lecointe,Ulrike Mäder,Pierre Nicolas,Sjouke Piersma,Frank Rügheimer,Dörte Becher,Philippe Bessières,Elena Bidnenko,Emma L. Denham,Etienne Dervyn,Kevin M. Devine,Geoff Doherty,Samuel Drulhe,Liza Felicori,Mark J. Fogg,Anne Goelzer,Annette Hansen,Colin R. Harwood,Michael Hecker,Sebastian Hubner,Claus Hultschig,Hanne Østergaard Jarmer,Edda Klipp,Aurélie Leduc,Peter J. Lewis,F. Molina,Philippe Noirot,Sabine Peres,Nathalie Pigeonneau,Susanne Pohl,Simon Rasmussen,Bernd Rinn,Marc Schaffer,Julian Schnidder,Benno Schwikowski,Jan Maarten van Dijl,Patrick Veiga,Sean Walsh,Anthony J. Wilkinson,Jörg Stelling,Stéphane Aymerich,Uwe Sauer +50 more
TL;DR: The responses of a bacterium to changing nutritional conditions are explored and an initial understanding of why certain regulatory strategies may be favored during evolution of dynamic control systems is offered.
Book ChapterDOI
Graphical Models for Industrial Planning on Complex Domains
TL;DR: Probabilistic graphical models, which have successfully been used for handling complex dependency structures and reasoning tasks in the presence of uncertainty, are dealt with.
Journal ArticleDOI
The Cyni framework for network inference in Cytoscape
TL;DR: Cyni, an open-source 'fill-in-the-algorithm' framework that provides common network inference functionality and user interface elements that allows the rapid transformation of Java-based network inference prototypes into apps of the popular open- source Cytoscape network analysis and visualization ecosystem.
Journal ArticleDOI
Fragmentation-free LC-MS can identify hundreds of proteins.
Pascal Bochet,Pascal Bochet,Frank Rügheimer,Frank Rügheimer,Tina Guina,Peter Brooks,Peter Brooks,David R. Goodlett,Peter Clote,Peter Clote,Peter Clote,Benno Schwikowski,Benno Schwikowski +12 more
TL;DR: The results suggest that additional developments in retention time prediction, measurement technology, and scoring algorithms may render fragmentation‐free approaches an interesting complement or an alternative to fragmentation‐based approaches.