G
Gary P. Kobinger
Researcher at Laval University
Publications - 130
Citations - 7825
Gary P. Kobinger is an academic researcher from Laval University. The author has contributed to research in topics: Ebola virus & Virus. The author has an hindex of 47, co-authored 130 publications receiving 6966 citations. Previous affiliations of Gary P. Kobinger include Canadian Science Centre for Human and Animal Health & University of Pennsylvania.
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Journal ArticleDOI
Taxonomy of the order Mononegavirales: update 2016
Claudio L. Afonso,Gaya K. Amarasinghe,Krisztián Bányai,Yīmíng Bào,Christopher F. Basler,Sina Bavari,Nicolás Bejerman,Kim R. Blasdell,François Xavier Briand,Thomas Briese,Alexander Bukreyev,Charles H. Calisher,Kartik Chandran,Jiāsēn Chéng,Anna N. Clawson,Peter L. Collins,Ralf G. Dietzgen,Olga Dolnik,Leslie L. Domier,Ralf Dürrwald,John M. Dye,Andrew J. Easton,Hideki Ebihara,Szilvia L. Farkas,Juliana Freitas-Astúa,Pierre Formenty,Ron A. M. Fouchier,Yanping Fu,Elodie Ghedin,Michael M. Goodin,Roger Hewson,Masayuki Horie,Timothy H. Hyndman,Dàohóng Jiāng,E. W. Kitajima,Gary P. Kobinger,Hideki Kondo,Gael Kurath,Robert A. Lamb,Sergio Lenardon,Eric M. Leroy,C. Li,Xian Dan Lin,Lìjiāng Liú,Ben Longdon,Szilvia Marton,Andrea Maisner,Elke Mühlberger,Sergey V. Netesov,Norbert Nowotny,Norbert Nowotny,Jean L. Patterson,Susan Payne,Janusz T. Paweska,Richard E. Randall,Bertus K. Rima,Paul A. Rota,Dennis Rubbenstroth,Martin Schwemmle,Mang Shi,Sophie J. Smither,Mark D. Stenglein,David M. Stone,Ayato Takada,Calogero Terregino,Robert B. Tesh,Jun Hua Tian,Keizo Tomonaga,Noël Tordo,Jonathan S. Towner,Nikos Vasilakis,Martin Verbeek,Viktor E. Volchkov,Victoria Wahl-Jensen,John A. Walsh,Peter J. Walker,David Wang,Lin-Fa Wang,Thierry Wetzel,Anna E. Whitfield,Jiǎtāo Xiè,Kwok-Yung Yuen,Yong-Zhen Zhang,Jens H. Kuhn +83 more
TL;DR: The updated taxonomy of the order Mononegavirales is presented as now accepted by the International Committee on Taxonomy of Viruses (ICTV).
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Successful Treatment of Ebola Virus–Infected Cynomolgus Macaques with Monoclonal Antibodies
Xiangguo Qiu,Jonathan Audet,Gary Wong,Stéphane Pillet,Alexander Bello,Teresa Cabral,Jim Strong,Frank Plummer,Cindy R. Corbett,Cindy R. Corbett,Judie B. Alimonti,Judie B. Alimonti,Gary P. Kobinger,Gary P. Kobinger +13 more
TL;DR: The present work shows that a combination of three neutralizing monoclonal antibodies directed against the Ebola envelope glycoprotein (GP) resulted in complete survival (four of four cynomolgus macaques) with no apparent side effects when three doses were administered 3 days apart beginning at 24 hours after a lethal challenge with EBOV.
Journal ArticleDOI
Nanozyme-strip for rapid local diagnosis of Ebola.
Demin Duan,Kelong Fan,Dexi Zhang,Shuguang Tan,Mifang Liang,Yang Liu,Jianlin Zhang,Panhe Zhang,Wei Liu,Xiangguo Qiu,Gary P. Kobinger,George F. Gao,Xiyun Yan +12 more
TL;DR: In this article, the authors used Fe3O4 magnetic nanoparticles (MNP) as a nano-probe to detect the glycoprotein of Ebola virus (EBOV) as low as 1 ng/mL, which is 100 times more sensitive than the standard strip method.
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A synthetic consensus anti–spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primates
Karuppiah Muthumani,Darryl Falzarano,Emma L. Reuschel,Colleen Tingey,Seleeke Flingai,Daniel O. Villarreal,Megan C. Wise,Ami Patel,Abdullah Izmirly,Abdulelah Aljuaid,Alecia M. Seliga,Geoff Soule,Matthew P. Morrow,Kimberly A. Kraynyak,Amir S. Khan,Dana P. Scott,Friederike Feldmann,Rachel A. LaCasse,Kimberly Meade-White,Atsushi Okumura,Kenneth E. Ugen,Niranjan Y. Sardesai,J. Joseph Kim,Gary P. Kobinger,Heinz Feldmann,David B. Weiner +25 more
TL;DR: It is demonstrated that a consensus MERS spike protein synthetic DNA vaccine can induce protective responses against viral challenge, indicating that this strategy may have value as a possible vaccine modality against this emerging pathogen.
Journal ArticleDOI
VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain
Andrea Marzi,Shelly J. Robertson,Elaine Haddock,Friederike Feldmann,Patrick W. Hanley,Dana P. Scott,James E. Strong,Gary P. Kobinger,Sonja M. Best,Heinz Feldmann +9 more
TL;DR: Preclinical proof is provided that VSV-EBOV completely protects macaques against lethal challenge with the West African EBOV-Makona strain, indicating that VS vesicular stomatitis virus may protect humans against E BOV infections in West Africa with relatively short time to immunity, promoting its use for immediate public health responses.