H
H-G Hwu
Researcher at National Taiwan University
Publications - 10
Citations - 644
H-G Hwu is an academic researcher from National Taiwan University. The author has contributed to research in topics: Schizophrenia (object-oriented programming) & Genetic linkage. The author has an hindex of 7, co-authored 10 publications receiving 601 citations.
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Journal ArticleDOI
Meta-analysis of 32 genome-wide linkage studies of schizophrenia
Mandy Y.M. Ng,Douglas F. Levinson,Stephen V. Faraone,Brian K. Suarez,Lynn E. DeLisi,Lynn E. DeLisi,Tadao Arinami,Brien P. Riley,Tiina Paunio,Tiina Paunio,A. E. Pulver,Irmansyah,Peter Holmans,Michael Escamilla,Dieter B. Wildenauer,Nigel Williams,Claudine Laurent,Bryan J. Mowry,Linda M. Brzustowicz,Michel Maziade,Pamela Sklar,D L Garver,Gonçalo R. Abecasis,Bernard Lerer,M D Fallin,Hugh Gurling,Pablo V. Gejman,Eva Lindholm,Hans W. Moises,William Byerley,Ellen M. Wijsman,Paola Forabosco,Ming T. Tsuang,Ming T. Tsuang,H-G Hwu,Yuji Okazaki,Kenneth S. Kendler,Brandon Wormley,Ayman H. Fanous,Ayman H. Fanous,Dermot Walsh,Francis A. O'Neill,Leena Peltonen,Gerald Nestadt,Virginia K. Lasseter,Kung-Yee Liang,G M Papadimitriou,Dimitris Dikeos,Sibylle G. Schwab,Michael John Owen,Michael Conlon O'Donovan,Nadine Norton,Elizabeth Hare,Henriette Raventós,Humberto Nicolini,Margot Albus,Wolfgang Maier,Vishwajit L. Nimgaonkar,Lars Terenius,J. Mallet,Melanie Jay,Stephanie Godard,Deborah A. Nertney,M. Alexander,Raymond R. Crowe,Jeremy M. Silverman,Anne S. Bassett,M-A Roy,Chantal Mérette,Carlos N. Pato,Michele T. Pato,J. Louw Roos,Yoav Kohn,Daniela Amann-Zalcenstein,Gursharan Kalsi,Andrew McQuillin,David Curtis,Jon Brynjolfson,Thordur Sigmundsson,Hannes Petursson,Alan R. Sanders,Jubao Duan,Elena Jazin,Marina Myles-Worsley,Maria Karayiorgou,Cathryn M. Lewis +85 more
TL;DR: The primary analysis met empirical criteria for ‘aggregate’ genome-wide significance, indicating that some or all of 10 bins are likely to contain loci linked to SCZ, including regions of chromosomes 1, 2q, 3q, 4q, 5q, 8p and 10q.
Journal ArticleDOI
Linkage of schizophrenia with chromosome 1q loci in Taiwanese families.
TL;DR: Evaluated the linkage of schizophrenia with markers of the 1q22–44 region in 52 Taiwanese families with at least two affected siblings to provide guidance for positional cloning studies on candidate genes in the 1Q22–31 and 1q41–44 regions.
Journal ArticleDOI
More evidence supports the association of PPP3CC with schizophrenia.
Yu-Li Liu,Cathy S.J. Fann,Chih-Min Liu,Chien-Ching Chang,Wei-Chih Yang,Shuen-Iu Hung,Shuen-Iu Hung,Sung-Liang Yu,Tzung-Jeng Hwang,Ming H. Hsieh,C-M Liu,Min-Min Tsuang,J Wu,Yuh-Shan Jou,Stephen V. Faraone,Ming T. Tsuang,Ming T. Tsuang,Wei J. Chen,H-G Hwu +18 more
TL;DR: The results suggest that PPP3CC gene may be a true susceptibility gene for schizophrenia.
Journal ArticleDOI
Aberrant expression of microRNAs as biomarker for schizophrenia: from acute state to partial remission, and from peripheral blood to cortical tissue.
Chi-Yu Lai,Lee Sy,Elizabeth Scarr,Yu Yh,Lin Yt,Chih-Min Liu,Hwang Tj,Ming H. Hsieh,Liu Cc,Yi-Ling Chien,Madhara Udawela,Andrew Gibbons,Andrew Gibbons,Ian P. Everall,Ian P. Everall,H-G Hwu,Brian Dean,Brian Dean,Wei J. Chen +18 more
TL;DR: The expression level of the sevenmiRNAs did not alter after ~2 months of hospitalization with significant improvement in clinical symptoms, suggesting the miRNAs could be traits rather than state-dependent markers, and unexpected increase in hsa-miR-34a expressions in human cortical but not subcortical region.
Journal ArticleDOI
A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12
R. E. Straub,Homero Vallada,David Curtis,P. C. Sham,Hiroshi Kunugi,J. H. Zhao,Robin M. Murray,P. McGuffin,Shinichiro Nanko,Michael John Owen,Michael Gill,David A. Collier,Stylianos E. Antonarakis,David E. Housman,Haig H. Kazazian,Gerald Nestadt,A. E. Pulver,C J MacLean,Dermot Walsh,Kenneth S. Kendler,Lynn E. DeLisi,Mihael H. Polymeropoulos,Hilary Coon,William Byerley,R. Lofthouse,Elliot S. Gershon,Lynn R. Goldin,Robert B. Freedman,Claudine Laurent,S. Bodeau-Pean,T. d'Amato,M. Jay,Dominique Campion,J. Mallet,D. B. Wildenauer,B. Lerer,Margot Albus,Manfred Ackenheil,Richard P. Ebstein,Joachim Hallmayer,Wolfgang Maier,Hugh Gurling,G Kalsi,J Brynjolfsson,T. Sigmundson,Hannes Petursson,D. H. R. Blackwood,W. Muri,D. StClair,L. He,S. Maguire,Hans W. Moises,H-G Hwu,L. Yang,Claudia Wiese,H. Kristbjarnarson,Douglas F. Levinson,Bryan J. Mowry,H. Donis-Keller,Nicholas K. Hayward,Raymond R. Crowe,Jeremy M. Silverman,Derek J. Nancarrow,C. M. Read +63 more
TL;DR: The transmission disequilibrium test (TDT) and additional parametric and non-parametric linkage analysis of the same data further strengthen the notion that there is a susceptibility locus for schizophrenia close to D22S278.