Harry C. Tjondro

TL;DR: The results suggested that the irreversible changes in oligomer size induced by various stresses might promote the membrane association of αA-crystallin and therefore might play a role in aged cataract.

TL;DR: This corrects the article to show that the H2O2/H2O/O2 balance is determined by a combination of H2A and O2 values, not necessarily reflecting a direct relationship between these numbers and each other.

TL;DR: In this paper, the potential of quantitative serum N-glycomics performed using porous graphitized carbon liquid chromatography tandem mass spectrometry to stratify bacteremic patients infected with Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Streptococcus viridans from healthy donors (n = 39).

TL;DR: This comprehensive neutrophil granule glycome map, the first of its kind, highlights novel granule-specific glycosylation features and is a crucial first step towards a better understanding of the mechanisms regulating protein glycosolation during neutrophils granulopoiesis and a more detailed understanding of neutrophIL biology and function.

TL;DR: Native mass spectrometry, mass photometry, and glycopeptide profiling revealed extreme molecular complexity of dimeric nMPO arising from heterogeneous glycosylation, oxidation, chlorination and polypeptide truncation variants, and a lower-abundance monomer, providing new insight into neutrophil glycobiology.