H
Helen M. Macdonald
Researcher at University of Aberdeen
Publications - 88
Citations - 5657
Helen M. Macdonald is an academic researcher from University of Aberdeen. The author has contributed to research in topics: Vitamin D and neurology & Population. The author has an hindex of 35, co-authored 88 publications receiving 5178 citations. Previous affiliations of Helen M. Macdonald include McGill University & Woolmanhill Hospital.
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Journal ArticleDOI
Common genetic determinants of vitamin D insufficiency: a genome-wide association study
Thomas J. Wang,Feng Zhang,J. Brent Richards,Bryan Kestenbaum,Joyce B. J. van Meurs,Diane J. Berry,Douglas P. Kiel,Elizabeth A. Streeten,Claes Ohlsson,Daniel L. Koller,Leena Peltonen,Leena Peltonen,Jason D. Cooper,Paul F. O'Reilly,Denise K. Houston,Nicole L. Glazer,Liesbeth Vandenput,Munro Peacock,Julia Shi,Fernando Rivadeneira,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,Pouta Anneli,Ian H. de Boer,Massimo Mangino,Bernet S. Kato,Deborah J. Smyth,Sarah L. Booth,Paul F. Jacques,Greg L. Burke,Mark O. Goodarzi,Ching-Lung Cheung,Myles Wolf,Kenneth Rice,David Goltzman,Nick Hidiroglou,Martin Ladouceur,Nicholas J. Wareham,Lynne J. Hocking,Deborah J. Hart,Nigel K Arden,Cyrus Cooper,Suneil Malik,William D. Fraser,Anna Liisa Hartikainen,Guangju Zhai,Helen M. Macdonald,Nita G. Forouhi,Ruth J. F. Loos,David M. Reid,Alan Hakim,Elaine M. Dennison,Yongmei Liu,Chris Power,Helen Stevens,Laitinen Jaana,Ramachandran S. Vasan,Nicole Soranzo,Nicole Soranzo,Jörg Bojunga,Bruce M. Psaty,Mattias Lorentzon,Tatiana Foroud,Tamara B. Harris,Albert Hofman,John-Olov Jansson,Jane A. Cauley,André G. Uitterlinden,Quince Gibson,Marjo-Riitta Järvelin,David Karasik,David S. Siscovick,Michael J. Econs,Stephen B. Kritchevsky,Jose C. Florez,John A. Todd,Josée Dupuis,Elina Hyppönen,Tim D. Spector +79 more
TL;DR: In this article, a genome-wide association study of 25-hydroxyvitamin D concentrations in 33,996 individuals of European descent from 15 cohorts was conducted to identify common genetic variants affecting vitamin D concentrations and risk of insufficiency.
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Nutritional associations with bone loss during the menopausal transition: evidence of a beneficial effect of calcium, alcohol, and fruit and vegetable nutrients and of a detrimental effect of fatty acids
TL;DR: Although menopausal status and hormone replacement therapy use dominate women's bone health, diet may influence early postmenopausal bone loss and fruit and vegetable intake may protect against premenopausal Bone mineral density loss.
Journal ArticleDOI
Effect of Vitamin D Supplementation on Blood Pressure: A Systematic Review and Meta-analysis Incorporating Individual Patient Data
Louise A. Beveridge,Allan D. Struthers,Faisel Khan,Rolf Jorde,Robert Scragg,Helen M. Macdonald,Jessica A. Alvarez,Rebecca S. Boxer,Andrea Dalbeni,Adam D. Gepner,Nicole M. Isbel,Thomas Larsen,Jitender Nagpal,William Petchey,Hans Stricker,Franziska Strobel,Vin Tangpricha,Laura Toxqui,M. Pilar Vaquero,Louise Wamberg,Armin Zittermann,Miles D. Witham +21 more
TL;DR: Vitamin D supplementation is ineffective as an agent for lowering BP and thus should not be used as an antihypertensive agent.
Journal ArticleDOI
Low dietary potassium intakes and high dietary estimates of net endogenous acid production are associated with low bone mineral density in premenopausal women and increased markers of bone resorption in postmenopausal women.
TL;DR: Dietary potassium, an indicator of NEAP and fruit and vegetable intake, may exert a modest influence on markers of bone health, which over a lifetime may contribute to a decreased risk of osteoporosis.
Journal ArticleDOI
Vitamin D3 Supplementation Has No Effect on Conventional Cardiovascular Risk Factors: A Parallel-Group, Double-Blind, Placebo-Controlled RCT
Adrian D. Wood,Karen R. Secombes,Frank Thies,Lorna Aucott,Alison J. Black,Alexandra Mavroeidi,William G. Simpson,William D. Fraser,David M. Reid,Helen M. Macdonald +9 more
TL;DR: Testing whether daily doses of vitamin D at 400 or 1000 IU/d for 1 yr affected conventional markers of cardiovascular disease (CVD) risk and improving vitamin D status through dietary supplementation is unlikely to reduce CVD risk factors.