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Hongjie Zhang

Researcher at Hong Kong Baptist University

Publications -  174
Citations -  4155

Hongjie Zhang is an academic researcher from Hong Kong Baptist University. The author has contributed to research in topics: Taxus & Chemistry. The author has an hindex of 35, co-authored 160 publications receiving 3405 citations. Previous affiliations of Hongjie Zhang include Xishuangbanna Tropical Botanical Garden & Chinese Academy of Sciences.

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Use of high-performance liquid chromatography-tandem mass spectrometry to distinguish Panax ginseng C. A. Meyer (Asian ginseng) and Panax quinquefolius L. (North American ginseng).

TL;DR: LC-MS-MS analysis of ginseng products for the presence and ratio of gINSenoside Rf and 24(R)-pseudoginsenoside F11 may be used for the unambiguous identification of Asian and North American ginsenengs.
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A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition

TL;DR: Curcumin derivative C1 is identified as a novel MTOR-independent activator of TFEB, which enhances autophagy and lysosome biogenesis in vitro and in vivo and is a potential therapeutic agent for the treatment of neurodegenerative diseases.
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Maoecrystal V, cytotoxic diterpenoid with a novel C19 skeleton from Isodon eriocalyx (Dunn.) hara.

TL;DR: Maoecrystal V, a novel C(19) diterpenoid possessing a unique 6,7-seco-6-nor-15(8-->9)-abeo-5,8-epoxy-ent-kaurane skeleton, was isolated from the leaves of a Chinese medicinal herb, Isodon eriocalyx and showed remarkable inhibitory activity toward HeLa cells.
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Bioactive constituents from roots of Bursera tonkinensis.

TL;DR: Of the 12 compounds isolated from the roots of Bursera tonkinensis Guillaum, only 4'-demethyldesoxypodophyllotoxin exhibited significant cytotoxic activities against KB, Col2 and LNCaP cell lines.
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Discovery of cyclooxygenase inhibitors from medicinal plants used to treat inflammation.

TL;DR: Eleven authenticated botanicals used in the traditional Chinese medicine Huo-Luo-Xiao-Ling Dan were screened for ligands to cyclooxygenase (COX) and the IC(50) values of most of these natural product ligands have not been reported previously.