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Jia-Hong Lu

Researcher at University of Macau

Publications -  139
Citations -  10430

Jia-Hong Lu is an academic researcher from University of Macau. The author has contributed to research in topics: Autophagy & Medicine. The author has an hindex of 32, co-authored 100 publications receiving 7512 citations. Previous affiliations of Jia-Hong Lu include Icahn School of Medicine at Mount Sinai & Hong Kong Baptist University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

Daniel J. Klionsky, +2983 more
- 08 Feb 2021 - 
TL;DR: In this article, the authors present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes.
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Berberine ameliorates β-amyloid pathology, gliosis, and cognitive impairment in an Alzheimer's disease transgenic mouse model

Siva Sundara Kumar Durairajan, +9 more
- 01 Dec 2012 - 
TL;DR: The results suggest that BBR provides neuroprotective effects in TgCRND8 mice through regulating APP processing and that further investigation of the BBR for therapeutic use in treating AD is warranted.
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Baicalein Inhibits Formation of α-Synuclein Oligomers within Living Cells and Prevents Aβ Peptide Fibrillation and Oligomerisation

Jia-Hong Lu, +9 more
- 07 Mar 2011 - 
TL;DR: Zhang et al. as discussed by the authors showed that Baicalein, a flavonoid extracted from the Chinese herbal medicine Scutellaria baicalensis Georgi ("huang qin" in Chinese), is a potent inhibitor of α-syn oligomerization both in cell-free and cellular systems.
Journal ArticleDOI

Isorhynchophylline, a natural alkaloid, promotes the degradation of alpha-synuclein in neuronal cells via inducing autophagy.

Jia-Hong Lu, +8 more
- 01 Jan 2012 - 
TL;DR: Data from this study raise the possibility that oxindole alkaloid derivatives may serve as a means to stimulate autophagy in neuronal cells, thereby exerting preventive and therapeutic values against neurodegenerative diseases such as Parkinson disease by reducing pathogenic protein aggregates in neurons.