J
J. Christopher Love
Researcher at Massachusetts Institute of Technology
Publications - 215
Citations - 20681
J. Christopher Love is an academic researcher from Massachusetts Institute of Technology. The author has contributed to research in topics: Antigen & Antibody. The author has an hindex of 55, co-authored 186 publications receiving 17873 citations. Previous affiliations of J. Christopher Love include University of Illinois at Urbana–Champaign & Harvard University.
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Journal ArticleDOI
Self-assembled monolayers of thiolates on metals as a form of nanotechnology.
Journal ArticleDOI
Improved pattern transfer in soft lithography using composite stamps
TL;DR: In this article, the preparation of two-layer stamps was adapted from a procedure originally developed by Schmid et al. (Macromolecules 2000, 33, 3042) for microcontact printing.
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Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput
Todd M. Gierahn,Marc H. Wadsworth,Marc H. Wadsworth,Marc H. Wadsworth,Travis K. Hughes,Travis K. Hughes,Travis K. Hughes,Bryan D. Bryson,Bryan D. Bryson,Andrew Butler,Rahul Satija,Sarah M. Fortune,Sarah M. Fortune,J. Christopher Love,J. Christopher Love,J. Christopher Love,Alex K. Shalek,Alex K. Shalek,Alex K. Shalek +18 more
TL;DR: Seq-Well is presented, a portable, low-cost platform for massively parallel single-cell RNA-seq that is used to profile thousands of primary human macrophages exposed to Mycobacterium tuberculosis.
Journal ArticleDOI
Scalable whole-exome sequencing of cell-free DNA reveals high concordance with metastatic tumors
Viktor A. Adalsteinsson,Viktor A. Adalsteinsson,Gavin Ha,Gavin Ha,Samuel S. Freeman,Samuel S. Freeman,Atish D. Choudhury,Daniel G. Stover,Heather A. Parsons,Gregory Gydush,Sarah C. Reed,Denisse Rotem,Justin Rhoades,Denis Loginov,Denis Loginov,Dimitri Livitz,Daniel Rosebrock,Daniel Rosebrock,Ignaty Leshchiner,Jaegil Kim,Chip Stewart,Mara Rosenberg,Joshua M. Francis,Joshua M. Francis,Cheng-Zhong Zhang,Cheng-Zhong Zhang,Ofir Cohen,Ofir Cohen,Coyin Oh,Huiming Ding,Paz Polak,Paz Polak,Max Lloyd,Sairah Mahmud,Karla Helvie,Margaret S. Merrill,Rebecca A. Santiago,Edward P. O’Connor,Seong Ho Jeong,Rachel Leeson,Rachel M. Barry,Joseph F. Kramkowski,Zhenwei Zhang,Laura Polacek,Jens G. Lohr,Jens G. Lohr,Molly Schleicher,Emily Lipscomb,Andrea Saltzman,Nelly Oliver,Lori Marini,Adrienne G. Waks,Adrienne G. Waks,Lauren C. Harshman,Sara M. Tolaney,Eliezer M. Van Allen,Eric P. Winer,Nan Lin,Mari Nakabayashi,Mary-Ellen Taplin,Cory M. Johannessen,Levi A. Garraway,Todd R. Golub,Jesse S. Boehm,Nikhil Wagle,Nikhil Wagle,Gad Getz,Gad Getz,J. Christopher Love,J. Christopher Love,Matthew Meyerson +70 more
TL;DR: In this paper, a software called ichorCNA was proposed to quantitatively measure tumor content in cfDNA from 0.1× coverage whole-genome sequencing data without prior knowledge of tumor mutations.
Journal ArticleDOI
A microengraving method for rapid selection of single cells producing antigen-specific antibodies.
J. Christopher Love,Jehnna L. Ronan,Gijsbert M. Grotenbreg,Annemarthe G. Van der Veen,Hidde L. Ploegh +4 more
TL;DR: A soft lithographic method based on intaglio printing to generate microarrays comprising the secreted products of single cells enabling a rapid and high-throughput system for identification, recovery and clonal expansion of cells producing antigen-specific antibodies.