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John J. Sakon

Researcher at University of Pennsylvania

Publications -  19
Citations -  749

John J. Sakon is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Recall & Episodic memory. The author has an hindex of 7, co-authored 17 publications receiving 603 citations. Previous affiliations of John J. Sakon include Center for Neural Science & College of William & Mary.

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Justify your alpha

Daniel Lakens, +98 more
TL;DR: In response to recommendations to redefine statistical significance to P ≤ 0.005, it is proposed that researchers should transparently report and justify all choices they make when designing a study, including the alpha level.
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Detecting the conformation of individual proteins in live cells

TL;DR: In this paper, single-molecule fluorescence resonance energy transfer (smFRET) is applied in live cells and reveals the conformational changes of individual SNARE proteins upon entering a SNARE complex.

Detecting the Conformation of Individual Proteins in Live Cells using Single Molecule Fluorescence Resonance Energy Transfer

John J. Sakon
TL;DR: Single-molecule fluorescence resonance energy transfer with single-particle tracking in live cells to detect the in vivo conformation of individual proteins shows the potential of this method to reveal dynamic interactions within cells.
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DNA methylation profiling in nanochannels

TL;DR: The profiling of the 5-methyl cytosine distribution within single genomic-sized DNA molecules at a gene-relevant resolution is reported, and single-molecule read-lengths exceeding 140 kbp have been achieved.
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Context-dependent incremental timing cells in the primate hippocampus

TL;DR: It is shown that individual primate hippocampal neurons not only track time, but do so only when specific contextual information (e.g., object identity/location) is cued.