K
Katherine K. Nishimura
Researcher at Fred Hutchinson Cancer Research Center
Publications - 31
Citations - 1524
Katherine K. Nishimura is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Medicine & Population. The author has an hindex of 14, co-authored 21 publications receiving 1048 citations. Previous affiliations of Katherine K. Nishimura include University of California, San Francisco & Washington University in St. Louis.
Papers
More filters
Journal ArticleDOI
Genetic analyses of diverse populations improves discovery for complex traits
Genevieve L. Wojcik,Mariaelisa Graff,Katherine K. Nishimura,Ran Tao,Jeffrey Haessler,Christopher R. Gignoux,Christopher R. Gignoux,Heather M. Highland,Yesha Patel,Elena P. Sorokin,Christy L. Avery,Gillian M. Belbin,Stephanie A. Bien,Iona Cheng,Sinead Cullina,Chani J. Hodonsky,Yao Hu,Laura M. Huckins,Janina M. Jeff,Anne E. Justice,Jonathan M. Kocarnik,Unhee Lim,Bridget M Lin,Yingchang Lu,Sarah C. Nelson,Sungshim L. Park,Hannah Poisner,Michael Preuss,Melissa A. Richard,Claudia Schurmann,Claudia Schurmann,Veronica Wendy Setiawan,Alexandra Sockell,Karan Vahi,Marie Verbanck,Abhishek Vishnu,Ryan W. Walker,Kristin L. Young,Niha Zubair,Victor Acuña-Alonso,José Luis Ambite,Kathleen C. Barnes,Eric Boerwinkle,Erwin P. Bottinger,Erwin P. Bottinger,Carlos Bustamante,Christian Caberto,Samuel Canizales-Quinteros,Matthew P. Conomos,Ewa Deelman,Ron Do,Kimberly F. Doheny,Lindsay Fernández-Rhodes,Lindsay Fernández-Rhodes,Myriam Fornage,Benyam Hailu,Gerardo Heiss,Brenna M. Henn,Lucia A. Hindorff,Rebecca D. Jackson,Cecelia A. Laurie,Cathy C. Laurie,Yuqing Li,Yuqing Li,Danyu Lin,Andrés Moreno-Estrada,Girish N. Nadkarni,Paul Norman,Loreall Pooler,Alexander P. Reiner,Jane Romm,Chiara Sabatti,Karla Sandoval,Xin Sheng,Eli A. Stahl,Daniel O. Stram,Timothy A. Thornton,Christina L. Wassel,Lynne R. Wilkens,Cheryl A. Winkler,Sachi Yoneyama,Steven Buyske,Christopher A. Haiman,Charles Kooperberg,Loic Le Marchand,Ruth J. F. Loos,Tara C. Matise,Kari E. North,Ulrike Peters,Eimear E. Kenny,Christopher S. Carlson +90 more
TL;DR: The value of diverse, multi-ethnic participants in large-scale genomic studies is demonstrated and evidence of effect-size heterogeneity across ancestries for published GWAS associations, substantial benefits for fine-mapping using diverse cohorts and insights into clinical implications are shown.
Journal ArticleDOI
Early-Life air pollution and asthma risk in minority children the GALA II and SAGE II studies
Katherine K. Nishimura,Joshua Galanter,Lindsey A. Roth,Sam S. Oh,Neeta Thakur,Elizabeth A. Nguyen,Shannon Thyne,Harold J. Farber,Denise Serebrisky,Rajesh Kumar,Emerita Brigino-Buenaventura,Adam Davis,Michael A. LeNoir,Kelley Meade,William Rodriguez-Cintron,Pedro C. Avila,Luisa N. Borrell,Kirsten Bibbins-Domingo,Jose R. Rodriguez-Santana,Śaunak Sen,Fred Lurmann,John R. Balmes,John R. Balmes,Esteban G. Burchard +23 more
TL;DR: Early-life NO₂ exposure is associated with childhood asthma in Latinos and African Americans, adding to a growing body of evidence that traffic-related pollutants may be causally related to childhood asthma.
Journal ArticleDOI
Genetic ancestry influences asthma susceptibility and lung function among Latinos
Maria Pino-Yanes,Neeta Thakur,Christopher R. Gignoux,Joshua Galanter,Lindsey A. Roth,Celeste Eng,Katherine K. Nishimura,Sam S. Oh,Hita Vora,Scott Huntsman,Elizabeth A. Nguyen,Donglei Hu,Katherine A. Drake,David V. Conti,Andrés Moreno-Estrada,Karla Sandoval,Cheryl A. Winkler,Luisa N. Borrell,Fred Lurmann,Talat Islam,Adam Davis,Harold J. Farber,Kelley Meade,Pedro C. Avila,Denise Serebrisky,Kirsten Bibbins-Domingo,Michael A. LeNoir,Jean G. Ford,Emerita Brigino-Buenaventura,William Rodriguez-Cintron,Shannon Thyne,Saunak Sen,Jose R. Rodriguez-Santana,Carlos Bustamante,L. Keoki Williams,Frank D. Gilliland,W. James Gauderman,Rajesh Kumar,Dara G. Torgerson,Esteban G. Burchard +39 more
TL;DR: For example, the authors found that Native American ancestry was associated with lower odds of asthma (OR = 0.72, 95% CI: 0.66-0.78, P ǫ= 8.0 × 10 −15 ), while African ancestry was significantly associated with higher odds of having asthma.
Journal ArticleDOI
Attenuated, flow-induced ATP release contributes to absence of flow-sensitive, purinergic Cai2+ signaling in human ADPKD cyst epithelial cells.
Chang Xu,Boris E. Shmukler,Katherine K. Nishimura,Elzbieta Kaczmarek,Sandro Rossetti,Peter C. Harris,Angela Wandinger-Ness,Robert L. Bacallao,Seth L. Alper +8 more
TL;DR: The loss of flow-induced, P2R-mediated Ca(i)2+ signaling in human ADPKD cyst epithelial cells was accompanied by reduced flow-sensitive ATP release, altered purinergic regulation of store-operated Ca2+ entry, and altered expression of gene products controlling extracellular nucleotide signaling.
Journal ArticleDOI
Calcium-Activated Potassium Channels Contribute to Human Coronary Microvascular Dysfunction After Cardioplegic Arrest
Jun Feng,Yuhong Liu,Richard T. Clements,Neel R. Sodha,Kamal R. Khabbaz,Venkatachalam Senthilnathan,Katherine K. Nishimura,Seth L. Alper,Frank W. Sellke +8 more
TL;DR: Novel mechanisms of endothelial and smooth muscle microvascular dysfunction after cardiac surgery are suggested, likely in part due to impaired function of SKCa and IKCa channels in the coronary microcirculation.