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Keagan Dunville
Researcher at Scuola Normale Superiore di Pisa
Publications - 4
Citations - 172
Keagan Dunville is an academic researcher from Scuola Normale Superiore di Pisa. The author has contributed to research in topics: Hippocampal formation & Biology. The author has an hindex of 2, co-authored 2 publications receiving 84 citations.
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Journal ArticleDOI
A community-based transcriptomics classification and nomenclature of neocortical cell types
Rafael Yuste,Michael Hawrylycz,Nadia Aalling,Argel Aguilar-Valles,Detlev Arendt,Rubén Armañanzas Arnedillo,Giorgio A. Ascoli,Concha Bielza,VS Bokharaie,Tobias Bergmann,Irina Bystron,Marco Capogna,YoonJeung Chang,Ann M. Clemens,Christiaan P. J. de Kock,Javier DeFelipe,Sandra E. Dos Santos,Keagan Dunville,Dirk Feldmeyer,Richárd Fiáth,Gordon Fishell,Angelica Foggetti,Xuefan Gao,Parviz Ghaderi,Natalia A. Goriounova,Onur Güntürkün,Kenta Hagihara,Vanessa Jane Hall,Moritz Helmstaedter,Suzana Herculano,Markus M. Hilscher,Hajime Hirase,Jens Hjerling-Leffler,Rebecca D. Hodge,Josh Huang,Rafiq Huda,Konstantin Khodosevich,Ole Kiehn,Henner Koch,Eric S. Kuebler,Malte Kühnemund,Pedro Larrañaga,Boudewijn P. F. Lelieveldt,Emma Louise Louth,Jan H. Lui,Huibert D. Mansvelder,Oscar Marín,Julio Martinez-Trujillo,Homeira Moradi Chameh,Alok Nath,Pavel Němec,Netanel Ofer,Ulrich Pfisterer,Samuel Pontes,William John Redmond,Jean Rossier,Joshua R. Sanes,Richard H. Scheuermann,Esther Serrano-Saiz,Jochen F. Steiger,Peter Somogyi,Gábor Tamás,Andreas S. Tolias,Maria Antonietta Tosches,Miguel Turrero García,Hermany Munguba Vieira,Christian Wozny,Thomas V. Wuttke,Liu Yong,Juan Yuan,Hongkui Zeng,Ed S. Lein +71 more
TL;DR: This work proposes the adoption of a transcriptome-based taxonomy of cell types for mammalian neocortex that should be hierarchical and use a standardized nomenclature, and could serve as an example for cell type atlases in other parts of the body.
Posted Content
A community-based transcriptomics classification and nomenclature of neocortical cell types.
Rafael Yuste,Michael Hawrylycz,Nadia Aalling,Detlev Arendt,Rubén Armañanzas,Giorgio A. Ascoli,Concha Bielza,VS Bokharaie,Tobias Bergmann,Irina Bystron,Marco Capogna,YoonJeung Chang,Ann M. Clemens,Christiaan P. J. de Kock,Javier DeFelipe,Sandra E. Dos Santos,Keagan Dunville,Dirk Feldmeyer,Richárd Fiáth,Gordon Fishell,Angelica Foggetti,Xuefan Gao,Parviz Ghaderi,Onur Güntürkün,Vanessa Jane Hall,Moritz Helmstaedter,Suzana Herculano-Houzel,Markus M. Hilscher,Hajime Hirase,Jens Hjerling-Leffler,Rebecca D. Hodge,Z. Josh Huang,Rafiq Huda,Yuan Juan,Konstantin Khodosevich,Ole Kiehn,Henner Koch,Eric S. Kuebler,Malte Kühnemund,Pedro Larrañaga,Boudewijn P. F. Lelieveldt,Emma Louise Louth,Jan H. Lui,Huibert D. Mansvelder,Oscar Marín,Julio Martinez-Trujillo,Homeira Moradi,Natalia A. Goriounova,Alok Nath Mohapatra,Pavel Němec,Netanel Ofer,Ulrich Pfisterer,Samuel Pontes,William John Redmond,Jean Rossier,Joshua R. Sanes,Richard H. Scheuermann,Esther Serrano Saiz,Peter Somogyi,Gábor Tamás,Andreas S. Tolias,Maria Antonietta Tosches,Miguel Turrero García,Argel Aguilar-Valles,Hermany Munguba,Christian Wozny,Thomas V. Wuttke,Liu Yong,Hongkui Zeng,Ed S. Lein +69 more
TL;DR: In this paper, the authors adopt a transcriptome-based taxonomy of the cell types in the adult mammalian neocortex, which is configured to flexibly incorporate new data from multiple approaches, developmental stages and a growing number of species, enabling improvement and revision of the classification.
Journal ArticleDOI
Laminin511 and WNT signalling sustain prolonged expansion of hiPSC-derived hippocampal progenitors.
Keagan Dunville,Fabrizio Tonelli,Elena Novelli,A. Codino,Verediana Massa,Annalisa Frontino,Silvia Giulia Galfrè,Francesca Biondi,Stefano Gustincich,Matteo Caleo,Luca Pandolfini,Claudia Alia,Federico Cremisi +12 more
TL;DR: By the timely re-activation of WNT signalling in neuralizing hiPSCs, neural progenitor cells with a gene expression profile typical of human embryonic dentate gyrus (DG) cells are produced and suggest that a niche of Laminin 511 and W NT signalling is sufficient to maintain their capability to undergo typical hippocampal neurogenesis.
Posted ContentDOI
Persistence of Cajal-Retzius cells in the postnatal hippocampus is required for development of dendritic spines of CA1 pyramidal cells
Ingvild Lynneberg Glærum,Keagan Dunville,Nicola P. Montaldo,H. Kirikae,Maximiliano José Nigro,Pål Sætrom,Barbara van Loon,Giulia Quattrocolo +7 more
TL;DR: This work specifically ablated CR cells from the postnatal hippocampus and highlighted layer-specific effects on dendritic spines and synaptic-related genes and revealed a critical role of CR cells in the establishment of the hippocampal network.