Sandra E. Dos Santos

TL;DR: The results suggest that Australasian marsupials have diverged from the ancestral Theria neuronal scaling rules, and support the suggestion that the scaling of average neuronal cell size with increasing numbers of neurons varies in evolution independently of the allocation of neurons across structures.

TL;DR: This work proposes the adoption of a transcriptome-based taxonomy of cell types for mammalian neocortex that should be hierarchical and use a standardized nomenclature, and could serve as an example for cell type atlases in other parts of the body.

TL;DR: The ratio between volumes of white and gray matter scales universally according to the same factors that account for the degree to which the cortex folds, that is, the combination of cortical surface area and thickness, as well as the clade-specific scaling of cortical thickness.

TL;DR: The addition of microglial cells to mammalian brains is governed by mechanisms that constrain the size of these cells and have remained conserved over 200 million years of mammalian evolution, suggesting that microglia-dependent functional recovery may be particularly difficult in those brain structures and species with high neuronal densities and therefore fewer microglian cells per neuron.

TL;DR: This paper showed that the restricted variation in size and distribution of glial cells has important consequences for neural tissue function that is aligned with their many fundamental roles being uncovered, and pointed to the possibility that this constraint is related to the late differentiation of the various glial cell types.