S
Satoshi Asai
Researcher at Nihon University
Publications - 146
Citations - 2973
Satoshi Asai is an academic researcher from Nihon University. The author has contributed to research in topics: Breath test & Medicine. The author has an hindex of 28, co-authored 130 publications receiving 2296 citations.
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Journal ArticleDOI
A cross-population atlas of genetic associations for 220 human phenotypes
Saori Sakaue,Masahiro Kanai,Yosuke Tanigawa,Juha Karjalainen,Mitja I. Kurki,Seizo Koshiba,Akira Narita,Takahiro Konuma,Kenichi Yamamoto,Masato Akiyama,Kazuyoshi Ishigaki,Akari Suzuki,Ken Suzuki,Wataru Obara,Ken Yamaji,Kazuhisa Takahashi,Satoshi Asai,Yasuo Takahashi,Takao Suzuki,Nobuaki Shinozaki,Hiroki Yamaguchi,Shiro Minami,Shigeo Murayama,Kozo Yoshimori,Satoshi Nagayama,Daisuke Obata,Masahiko Higashiyama,Akihide Masumoto,Yukihiro Koretsune,FinnGen,Kaoru Ito,Chikashi Terao,Toshimasa Yamauchi,Issei Komuro,Takashi Kadowaki,Gen Tamiya,Masayuki Yamamoto,Yusuke Nakamura,Yusuke Nakamura,Michiaki Kubo,Yoshinori Murakami,Kazuhiko Yamamoto,Yoichiro Kamatani,Aarno Palotie,Aarno Palotie,Aarno Palotie,Manuel A. Rivas,Mark J. Daly,Koichi Matsuda,Yukinori Okada +49 more
TL;DR: In this paper, the authors conducted 220 deep-phenotype genome-wide association studies (diseases, biomarkers and medication usage) in BioBank Japan (n = 179,000), by incorporating past medical history and text-mining of electronic medical records.
Journal ArticleDOI
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases
Kazuyoshi Ishigaki,Kazuyoshi Ishigaki,Masato Akiyama,Masahiro Kanai,Masahiro Kanai,Atsushi Takahashi,Eiryo Kawakami,Hiroki Sugishita,Saori Sakaue,Saori Sakaue,Nana Matoba,Siew-Kee Low,Yukinori Okada,Chikashi Terao,Tiffany Amariuta,Tiffany Amariuta,Steven Gazal,Steven Gazal,Yuta Kochi,Momoko Horikoshi,Ken Suzuki,Ken Suzuki,Kaoru Ito,Satoshi Koyama,Kouichi Ozaki,Shumpei Niida,Yasushi Sakata,Yasuhiko Sakata,Takashi Kohno,Kouya Shiraishi,Yukihide Momozawa,Makoto Hirata,Koichi Matsuda,Masashi Ikeda,Nakao Iwata,Shiro Ikegawa,Ikuyo Kou,Toshihiro Tanaka,Hidewaki Nakagawa,Akari Suzuki,Tomomitsu Hirota,Mayumi Tamari,Kazuaki Chayama,Daiki Miki,Masaki Mori,Satoshi Nagayama,Yataro Daigo,Yataro Daigo,Yoshio Miki,Toyomasa Katagiri,Osamu Ogawa,Wataru Obara,Hidemi Ito,Teruhiko Yoshida,Issei Imoto,Takashi Takahashi,Chizu Tanikawa,Takao Suzuki,Nobuaki Sinozaki,Shiro Minami,Hiroki Yamaguchi,Satoshi Asai,Yasuo Takahashi,Ken Yamaji,Kazuhisa Takahashi,Tomoaki Fujioka,Ryo Takata,Hideki Yanai,Akihide Masumoto,Yukihiro Koretsune,Hiromu Kutsumi,Masahiko Higashiyama,Shigeo Murayama,Naoko Minegishi,Kichiya Suzuki,Kozo Tanno,Atsushi Shimizu,Taiki Yamaji,Motoki Iwasaki,Norie Sawada,Hirokazu Uemura,Hirokazu Uemura,Keitaro Tanaka,Mariko Naito,Mariko Naito,Makoto Sasaki,Kenji Wakai,Shoichiro Tsugane,Masayuki Yamamoto,Kazuhiko Yamamoto,Yoshinori Murakami,Yusuke Nakamura,Soumya Raychaudhuri,Soumya Raychaudhuri,Soumya Raychaudhuri,Johji Inazawa,Toshimasa Yamauchi,Takashi Kadowaki,Michiaki Kubo,Yoichiro Kamatani +99 more
TL;DR: A large-scale genome-wide association study in a Japanese population provides insights into the etiology of complex diseases and highlights the importance of performing GWAS in non-European populations.
Journal Article
Vitamin D3 up-regulated protein 1 (VDUP1) expression in gastrointestinal cancer and its relation to stage of disease
Masahito Ikarashi,Yasuo Takahashi,Yukimoto Ishii,Toshihito Nagata,Satoshi Asai,Koichi Ishikawa +5 more
TL;DR: TaqMan RT-PCR assay results suggest a possible role of VDUP1 in the pathogenesis of gastrointestinal cancer, as well as its clinical significance.
Journal ArticleDOI
Leveraging fine-mapping and multi-population training data to improve cross-population polygenic risk scores
Omer Weissbrod,Masahiro Kanai,Huwenbo Shi,Steven Gazal,Wouter J. Peyrot,Amit Khera,Yukinori Okada,Koichi Matsuda,Yuji Yamanashi,Yoichi Furukawa,Takayuki Morisaki,Yoshinori Murakami,Yoichiro Kamatani,Kaori Muto,Akiko Nagai,Wataru Obara,Ken Yamaji,Kazuhisa Takahashi,Satoshi Asai,Yasuo Takahashi,Takao Suzuki,Nobuaki Sinozaki,Hiroki Yamaguchi,Shiro Minami,Shigeo Murayama,Kozo Yoshimori,Satoshi Nagayama,Daisuke Obata,Masahiko Higashiyama,Akihide Masumoto,Yukihiro Koretsune,Alicia R. Martin,Hilary K. Finucane,Alkes L. Price +33 more
TL;DR: PolyPred as mentioned in this paper leverages functionally informed fine-mapping to estimate causal effects (instead of tagging effects), addressing linkage disequilibrium differences, and BOLT-LMM, a published predictor.
Journal Article
Thymidylate synthase expression correlates closely with E2F1 expression in colon cancer.
Mitsuko Kasahara,Yasuo Takahashi,Toshihito Nagata,Satoshi Asai,Teruo Eguchi,Yukimoto Ishii,Masashi Fujii,Koichi Ishikawa +7 more
TL;DR: In this article, the relationship between the expressions of the Thymidylate Synthase (TS) gene and E2F1 transcription factor in primary colon cancer specimens remains unclear.