Margaret Herre

TL;DR: An improved, fully re-annotated Aedes aegypti genome assembly (AaegL5) provides insights into the sex-determining M locus, chemosensory systems that help mosquitoes to hunt humans and loci involved in insecticide resistance and will help to generate intervention strategies to fight this deadly disease vector.

TL;DR: Al Alteration of Rb fox targets in some autistic brains is correlated with downregulation of all three Rbfox proteins, supporting the potential clinical relevance of the splicing-regulatory network.

TL;DR: The genome-wide analysis of nElavl targets reveals that one function of neuron-specific RNABPs is to control excitation-inhibition balance in the brain, and these controls converge on the glutamate synthesis pathway in neurons.

TL;DR: It is concluded that loss of FMRP results in significant epigenetic misregulation and that targeting transcription via epigenetic regulators like Brd4 may provide new treatments for FXS.

TL;DR: Aedes aegypti uses a different organizational principle, with many neurons co-expressing multiple chemosensory receptor genes as mentioned in this paper , and the broad ligand-sensitivity of mosquito olfactory neurons depends on this non-canonical co-expression.