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Marieke C. J. Dekker

Researcher at Radboud University Nijmegen

Publications -  62
Citations -  5172

Marieke C. J. Dekker is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Parkinsonism & Population. The author has an hindex of 18, co-authored 54 publications receiving 4730 citations. Previous affiliations of Marieke C. J. Dekker include Netherlands Cancer Institute & Radboud University Nijmegen Medical Centre.

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Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism

Vincenzo Bonifati, +19 more
- 10 Jan 2003 - 
TL;DR: It is shown that DJ-1 mutations are associated with PARK7, a monogenic form of human parkinsonism, and these findings indicate that loss ofDJ-1 function leads to neurodegeneration.
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PARK7, a Novel Locus for Autosomal Recessive Early-Onset Parkinsonism, on Chromosome 1p36

C M van Duijn, +12 more
- 01 Sep 2001 - 
TL;DR: It is concluded that on chromosome 1 a second locus, PARK7, involved in autosomal recessive, early-onset parkinsonism is identified.
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Abnormal myotonic dystrophy protein kinase levels produce only mild myopathy in mice

G Jansen, +16 more
- 01 Jul 1996 - 
TL;DR: The contention that simple loss– or gain–of–expression of DMPK is not the only crucial requirement for development of the disease is strengthened.
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FBXO7 mutations cause autosomal recessive, early-onset parkinsonian- pyramidal syndrome

A. Di Fonzo, +16 more
- 20 Jan 2009 - 
TL;DR: It is conclusively show that recessive FBXO7 mutations cause progressive neurodegeneration with extrapyramidal and pyramidal system involvement, delineating a novel genetically defined entity that is proposed to designate as PARK15.
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Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study

Davina J. Hensman Moss, +734 more
- 01 Sep 2017 - 
TL;DR: A novel measure of disease progression and a genome-wide significant signal on chromosome 5 spanning three genes: MSH3, DHFR, and MTRNR2L2 is generated, suggesting this mechanism as an area for future therapeutic investigation.