M
Melissa Assel
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 83
Citations - 2166
Melissa Assel is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Medicine & Prostate cancer. The author has an hindex of 21, co-authored 68 publications receiving 1524 citations.
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Journal ArticleDOI
Copy number alteration burden predicts prostate cancer relapse
Haley Hieronymus,Nikolaus Schultz,Anuradha Gopalan,Brett S. Carver,Matthew T. Chang,Yonghong Xiao,Adriana Heguy,Kety Huberman,Melanie Bernstein,Melissa Assel,Rajmohan Murali,Andrew J. Vickers,Peter T. Scardino,Chris Sander,Victor E. Reuter,Barry S. Taylor,Charles L. Sawyers +16 more
TL;DR: It is demonstrated that copy number alteration (CNA) burden, a measure of the fraction of a tumor genome that is copy number altered, is prognostic for recurrence and metastasis and can be measured in diagnostic needle biopsies using low-input whole-genome sequencing, setting the stage for studies of prognostic impact in conservatively treated cohorts.
Journal ArticleDOI
Targeted Prostate Cancer Screening in BRCA1 and BRCA2 Mutation Carriers: Results from the Initial Screening Round of the IMPACT Study
Elizabeth Bancroft,Elizabeth Page,Elena Castro,Hans Lilja,Andrew J. Vickers,Daniel Sjöberg,Melissa Assel,Christopher S. Foster,Gillian Mitchell,Kate Drew,Lovise Maehle,Karol Axcrona,D. Gareth Evans,Barbara Bulman,Diana Eccles,Donna McBride,Christi J. van Asperen,Hans F. A. Vasen,Lambertus A. Kiemeney,Janneke Ringelberg,Cezary Cybulski,Dominika Wokołorczyk,Christina G. Selkirk,Peter J. Hulick,Anders Bojesen,Anne-Bine Skytte,Jimmy Lam,Louise Taylor,Rogier A. Oldenburg,Ruben Cremers,Gerald W. Verhaegh,Wendy A. G. van Zelst-Stams,Jan C. Oosterwijk,Ignacio Blanco,Mónica Salinas,Jackie Cook,Derek J. Rosario,Saundra S. Buys,Tom Conner,Margreet G. E. M. Ausems,Kai Ren Ong,Jonathan Hoffman,Susan M. Domchek,Jacquelyn Powers,Manuel R. Teixeira,Sofia Maia,William D. Foulkes,Nassim Taherian,Marielle W. G. Ruijs,Apollonia T.J.M. Helderman van den Enden,Louise Izatt,Rosemarie Davidson,Muriel A. Adank,Lisa Walker,Rita K. Schmutzler,Katherine M. Tucker,Judy Kirk,Shirley Hodgson,Marion Harris,Fiona Douglas,Geoffrey J. Lindeman,Janez Zgajnar,Marc Tischkowitz,Virginia E. Clowes,Rachel Susman,Teresa Ramón y Cajal,Nicholas Patcher,Nicholas Patcher,Neus Gadea,Allan D. Spigelman,Theo A. M. van Os,Annelie Liljegren,Lucy Side,Carole Brewer,Angela F. Brady,Alan Donaldson,Vigdis Stefansdottir,Eitan Friedman,Rakefet Chen-Shtoyerman,David J. Amor,Lucia Copakova,Julian Barwell,Veda N. Giri,Vedang Murthy,Nicola Nicolai,Soo Hwang Teo,Lynn Greenhalgh,Sara S. Strom,Alex Henderson,John S. McGrath,David J. Gallagher,Neil K. Aaronson,Audrey Ardern-Jones,Chris H. Bangma,David P. Dearnaley,Philandra Costello,Jorunn E. Eyfjord,Jeanette Rothwell,Alison Falconer,Henrik Grönberg,Freddie C. Hamdy,Oskar T. Johannsson,Vincent Khoo,Zsofia Kote-Jarai,Jan Lubinski,Ulrika Axcrona,J Melia,Joanne McKinley,A. Mitra,Clare Moynihan,Gad Rennert,Mohnish Suri,Penny Wilson,Emma Killick,Sue Moss,Rosalind A. Eeles +115 more
TL;DR: The IMPACT screening network is an international consortium of 62 centres in 20 countries evaluating the use of targeted PCa screening in men with BRCA1/2 mutations.
Journal ArticleDOI
Comparison Between the Four-kallikrein Panel and Prostate Health Index for Predicting Prostate Cancer
TL;DR: Two blood tests, the Prostate Health Index and the four-kallikrein panel, performed similarly and could both aid in decision making among Swedish men undergoing a prostate biopsy and similarly improved discrimination when predicting PCa and high-grade PCa.
Journal ArticleDOI
Interim Results from the IMPACT Study: Evidence for Prostate-specific Antigen Screening in BRCA2 Mutation Carriers
Elizabeth Page,Elizabeth Bancroft,Mark N. Brook,Melissa Assel,Mona Hassan Al Battat,Sarah Thomas,Natalie Taylor,Anthony Chamberlain,Jennifer Pope,Holly Ni Raghallaigh,D. Gareth Evans,Jeanette Rothwell,Lovise Maehle,Eli Marie Grindedal,Paul A. James,Paul A. James,Paul A. James,Lyon Mascarenhas,Joanne McKinley,Lucy Side,Tessy Thomas,Christi J. van Asperen,Hans F. A. Vasen,Lambertus A. Kiemeney,Janneke Ringelberg,Thomas Dyrso Jensen,Palle Jørn Sloth Osther,Brian T. Helfand,Elena Genova,Rogier A. Oldenburg,Cezary Cybulski,Dominika Wokołorczyk,Kai-ren Ong,Camilla Huber,Jimmy Lam,Louise Taylor,Mónica Salinas,Lídia Feliubadaló,Jan C. Oosterwijk,Wendy A. G. van Zelst-Stams,Jackie Cook,Derek J. Rosario,Susan M. Domchek,Jacquelyn Powers,Saundra S. Buys,Karen O’Toole,Margreet G. E. M. Ausems,Rita K. Schmutzler,Kerstin Rhiem,Louise Izatt,Vishakha Tripathi,Manuel R. Teixeira,Marta Cardoso,William D. Foulkes,William D. Foulkes,Armen Aprikian,Heleen van Randeraad,Rosemarie Davidson,Mark Longmuir,Marielle W. G. Ruijs,Apollonia T.J.M. Helderman van den Enden,Muriel A. Adank,Rachel Williams,Lesley Andrews,Declan G. Murphy,Declan G. Murphy,Dorothy Halliday,Lisa Walker,Annelie Liljegren,Stefan Carlsson,Ashraf Azzabi,Irene Jobson,Catherine Morton,Kylie Shackleton,Katie Snape,Helen Hanson,Marion Harris,Marc Tischkowitz,Amy E Taylor,Judy Kirk,Judy Kirk,Rachel Susman,Rakefet Chen-Shtoyerman,Allan D. Spigelman,Allan D. Spigelman,Nicholas Pachter,Nicholas Pachter,Munaza Ahmed,Teresa Ramón y Cajal,Janez Zgajnar,Carole Brewer,Carole Brewer,Neus Gadea,Angela F. Brady,Theo A. M. van Os,David J. Gallagher,Oskar T. Johannsson,Alan Donaldson,Julian Barwell,Nicola Nicolai,Eitan Friedman,Elias Obeid,Lynn Greenhalgh,Vedang Murthy,Lucia Copakova,Sibel Saya,John S. McGrath,John S. McGrath,Peter Cooke,Karina Rønlund,Kate Richardson,Alex Henderson,Soo Hwang Teo,Banu Arun,Karin Kast,Alexander Dias,Neil K. Aaronson,Audrey Ardern-Jones,Chris H. Bangma,Elena Castro,David P. Dearnaley,Diana Eccles,Diana Eccles,K. Tricker,Jorunn E. Eyfjord,Alison Falconer,Christopher S. Foster,Henrik Grönberg,Freddie C. Hamdy,Freddie C. Hamdy,Vigdis Stefansdottir,Vincent Khoo,Geoffrey J. Lindeman,Geoffrey J. Lindeman,Geoffrey J. Lindeman,Jan Lubinski,Karol Axcrona,Christos Mikropoulos,Anita Mitra,Clare Moynihan,Gadi Rennert,Mohnish Suri,Penny Wilson,Tim Dudderidge,Judith Offman,Zsofia Kote-Jarai,Andrew J. Vickers,Hans Lilja,Hans Lilja,Hans Lilja,Rosalind A. Eeles +150 more
TL;DR: After 3 yr of prostate-specific antigen (PSA) testing, it is demonstrated that after 3’yr of screening, more serious prostate cancers are detected in men with BRCA2 mutations than in those without these mutations.
Journal ArticleDOI
Guidelines for Reporting of Statistics for Clinical Research in Urology.
Melissa Assel,Daniel Sjöberg,Andrew Elders,Xuemei Wang,Dezheng Huo,Albert Botchway,Kristin Delfino,Yunhua Fan,Zhiguo Zhao,Tatsuki Koyama,Brent K. Hollenbeck,Rui Qin,Whitney E. Zahnd,Emily C. Zabor,Michael W. Kattan,Andrew J. Vickers +15 more
TL;DR: Investigators submitting clinical research to European Urology are encouraged to follow guidelines for the reporting of statistics, which will increase the quality of published papers, and improve statistical knowledge in urology in general.