M
Michael Detmar
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 351
Citations - 43193
Michael Detmar is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Lymphatic system & Lymphangiogenesis. The author has an hindex of 94, co-authored 334 publications receiving 39086 citations. Previous affiliations of Michael Detmar include Harvard University & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis
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Transcriptional profiling of breast cancer-associated lymphatic vessels reveals VCAM-1 as regulator of lymphatic invasion and permeability.
Lothar C. Dieterich,Kübra Kapaklikaya,Timur Cetintas,Steven T. Proulx,Catharina D. Commerford,Kristian Ikenberg,Samia B. Bachmann,Jeannette Scholl,Michael Detmar +8 more
TL;DR: Analysis of tumor‐associated LECs directly isolated from the primary tumor in an orthotopic mouse model of triple negative breast cancer suggests that disruption of lymphatic junctions and increased permeability via tumor‐induced lymphatic VCAM‐1 expression may represent a new target to block lymphatic invasion and metastasis.
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A Novel Role for Microphthalmia-Associated Transcription Factor–Regulated Pigment Epithelium-Derived Factor during Melanoma Progression
Soheil S. Dadras,Richard J. Lin,Gita Razavi,Akinori Kawakami,Jinyan Du,Erez Feige,Danny A. Milner,Massimo Loda,Scott R. Granter,Michael Detmar,Hans R. Widlund,Martin A. Horstmann,David E. Fisher +12 more
TL;DR: It is suggested that loss of PEDF expression promotes early invasive melanoma growth.
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Lymphatics in nanophysiology.
TL;DR: Assessments of the lymphatic function at nano-scale levels address the major contribution of lymphatic vessels to the kinetics of drug delivery and excretion in physiological and pathological settings.
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Retinoids and keratinocyte differentiation in vitro.
TL;DR: It was found that the second generation of retinoids had a lower antikeratinizing potential than the third generation ofretinoids and it should be more useful to employ arotinoid acid or arot inoid sulfone rather than arotInoid in clinical psoriasis studies.