M
Michael Detmar
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 351
Citations - 43193
Michael Detmar is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Lymphatic system & Lymphangiogenesis. The author has an hindex of 94, co-authored 334 publications receiving 39086 citations. Previous affiliations of Michael Detmar include Harvard University & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
Isolation of human sebaceous glands and cultivation of sebaceous gland-derived cells as an in vitro model.
Longqing Xia,Christos C. Zouboulis,Michael Detmar,Augusto Mayer-da-Silva,Rudolf Stadler,Constantin E. Orfanos +5 more
TL;DR: The cultured cells preserved in vitro morphologic characteristics and differentiation patterns comparable to those described for normal human sebocytes in vivo, with a high rate of viable cells.
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Lymphatic invasion in cutaneous melanoma is associated with sentinel lymph node metastasis
Katie Doeden,Zhihai Ma,Balasubramanian Narasimhan,Susan M. Swetter,Susan M. Swetter,Michael Detmar,Soheil S. Dadras +6 more
TL;DR: This data indicates that Sentinel lymph node metastasis is a major determinant for staging, prognostication and clinical management of patients with cutaneous melanoma and the role of lymphatic vs. vascular invasion for SLN spread remains unclear.
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Ultraviolet B-Induced Skin Angiogenesis Is Associated with a Switch in the Balance of Vascular Endothelial Growth Factor and Thrombospondin-1 Expression
TL;DR: The results demonstrate that acute UVB irradiation leads to a shift toward a proangiogenic environment and they suggest that the balance between VEGF and TSP-1 plays a critical role in the control of angiogenesis and vascular regression induced by acute UV B irradiation.
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Lymphatic vessels: new targets for the treatment of inflammatory diseases
TL;DR: Surprisingly, activation of lymphatic vessel function by delivery of vascular endothelial growth factor-C exerts anti-inflammatory effects in several models of cutaneous and joint inflammation.
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Inhibition of Chronic and Acute Skin Inflammation by Treatment with a Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor
Cornelia Halin,Hermann Fahrngruber,Josef G. Meingassner,Guido Bold,Amanda Littlewood-Evans,Anton Stuetz,Michael Detmar +6 more
TL;DR: Results demonstrate for the first time that VEGF receptor tyrosine-kinase inhibitors might be used to treat patients with inflammatory skin disorders such as psoriasis.