M
Michael Detmar
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 351
Citations - 43193
Michael Detmar is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Lymphatic system & Lymphangiogenesis. The author has an hindex of 94, co-authored 334 publications receiving 39086 citations. Previous affiliations of Michael Detmar include Harvard University & Beth Israel Deaconess Medical Center.
Papers
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Journal ArticleDOI
LETR1 is a lymphatic endothelial-specific lncRNA governing cell proliferation and migration through KLF4 and SEMA3C.
Luca Ducoli,Saumya Agrawal,Eliane Sibler,Tsukasa Kouno,Carlotta Tacconi,Chung-Chao Hon,Simone D. Berger,Daniela Müllhaupt,Yuliang He,Kim Jihye,Marco D’Addio,Lothar C. Dieterich,Piero Carninci,Michiel J. L. de Hoon,Jay W. Shin,Michael Detmar +15 more
TL;DR: In this article, a comprehensive map of lineage-specific lncRNAs in human dermal lymphatic and blood vascular endothelial cells (LECs and BECs) was determined, combining RNA-Seq and CAGESeq.
Journal ArticleDOI
Multidisciplinary Consideration of Potential Pathophysiologic Mechanisms of Paradoxical Erythema with Topical Brimonidine Therapy
James R. Docherty,Martin Steinhoff,Dianne Lorton,Michael Detmar,Gregor Schäfer,Anna D. Holmes,Anna Di Nardo +6 more
TL;DR: Attention to optimizing skin barrier function, setting patient expectations, and strategies to minimize potential problems may possibly reduce further the number of patients who experience side effects.
Patent
Thrombospondin-2 and uses thereof
Michael Detmar,Michael Streit +1 more
TL;DR: In this article, a method for treating a disorder characterized by unwanted angiogenesis and/or unwanted cellular proliferation, e.g., unwanted skin or prostate cell proliferation, by increasing a TSP-2 activity was presented.
Journal ArticleDOI
Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function.
Samuel Babity,Anna Polomska,Frédéric Couture,Mathias Bonmarin,Daniel Fehr,Michael Detmar,Davide Brambilla +6 more
TL;DR: This work demonstrates that this proposed method of using microneedles to deliver a near-infrared (NIR) fluorescent tattoo to the skin is compatible with a custom-made portable fluorescence measurement device and able to discriminate between drainage and lack of drainage in vivo in rats.
Book ChapterDOI
The role of neuropilin-1/semaphorin 3A signaling in lymphatic vessel development and maturation.
TL;DR: The role of semaphorins and their receptors in angiogenesis and lymphangiogenesis is summarized, with an emphasis on neuropilin-1/semaphorin 3A interactions in lymphatic vessel maturation and valve formation.