M
Michael Detmar
Researcher at École Polytechnique Fédérale de Lausanne
Publications - 351
Citations - 43193
Michael Detmar is an academic researcher from École Polytechnique Fédérale de Lausanne. The author has contributed to research in topics: Lymphatic system & Lymphangiogenesis. The author has an hindex of 94, co-authored 334 publications receiving 39086 citations. Previous affiliations of Michael Detmar include Harvard University & Beth Israel Deaconess Medical Center.
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Pathways TargetingTumor Lymphangiogenesis
TL;DR: The Vascular endothelial growth factor-C (VEGF-C) and VEGF-D were the first specific lymphangiogenesis factors identified, acting predominantly via VEG- receptor-3 (VEGFR-3) that is expressed by lymphatic endothelial cells, and a large number of clinical studies have shown a correlation between tumor expression of VEGFs and lymph node metastasis.
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Sialoglycans on lymphatic endothelial cells augment interactions with Siglec-1 (CD169) of lymph node macrophages
Marco D'Addio,Jasmin Frey,Carlotta Tacconi,Catharina D. Commerford,Cornelia Halin,Michael Detmar,Richard D. Cummings,Vivianne I. Otto +7 more
TL;DR: In this paper, the role of sialoglycans on lymphatic endothelial cells (LEC) in interactions with macrophage-expressed Siglec-1 (CD169) was explored.
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Quantitative histological analyses and transcriptional profiling reveal structural and molecular changes of the dermal extracellular matrix in cellulite.
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Mapping the lymphatic system across body scales and expertise domains: A report from the 2021 National Heart, Lung, and Blood Institute workshop at the Boston Lymphatic Symposium
Dhruv Singhal,Katy Börner,Elliot L. Chaikof,Michael Detmar,Maija Hollmén,Jeffrey J. Iliff,Maxim Itkin,Taija Makinen,Guillermo Oliver,Timothy P. Padera,Ellen M. Quardokus,Andrea J. Radtke,Hiroo Suami,Griffin M. Weber,Ilsa I. Rovira,Selen C. Muratoglu,Zorina S. Galis +16 more
TL;DR: In this article , the authors summarized current knowledge of the lymphatic system and identified prevailing challenges and opportunities to advance the field of lymphatic research as discussed by the experts in the workshop.