M
Michael Melkonian
Researcher at Max Planck Society
Publications - 287
Citations - 19732
Michael Melkonian is an academic researcher from Max Planck Society. The author has contributed to research in topics: Basal body & Photobioreactor. The author has an hindex of 69, co-authored 280 publications receiving 17300 citations. Previous affiliations of Michael Melkonian include University of Cologne & University of Münster.
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Journal ArticleDOI
Independent optical excitation of distinct neural populations
Nathan C. Klapoetke,Yasunobu Murata,Sung Soo Kim,Stefan R. Pulver,Amanda Birdsey-Benson,Yong Ku Cho,Tania K. Morimoto,Amy S. Chuong,Eric J. Carpenter,Zhijian Tian,Jun Wang,Yinlong Xie,Zhixiang Yan,Yong Zhang,Brian Y. Chow,Barbara Surek,Michael Melkonian,Vivek Jayaraman,Martha Constantine-Paton,Gane Ka-Shu Wong,Edward S. Boyden +20 more
TL;DR: Two channelrhodopsins, Chronos and Chrimson, are described, discovered through sequencing and physiological characterization of opsins from over 100 species of alga, that enable two-color activation of neural spiking and downstream synaptic transmission in independent neural populations without detectable cross-talk in mouse brain slice.
Independent optical excitation of distinct neural populations
Nathan C. Klapoetke,Yasunobu Murata,Sung Soo Kim,Stefan R. Pulver,Amanda Birdsey-Benson,Yong Ku Cho,Tania K. Morimoto,Amy S. Chuong,Eric J. Carpenter,Zhijian Tian,Jun Wang,Yinlong Xie,Zhixiang Yan,Yong Zhang,Brian Y. Chow,Barbara Surek,Michael Melkonian,Vivek Jayaraman,Martha Constantine-Paton,Gane Ka-Shu Wong,Edward S. Boyden +20 more
TL;DR: Chronos and Chrimson as mentioned in this paper have been shown to enable two-color activation of neural spiking and downstream synaptic transmission in independent neural populations without detectable cross-talk in mouse brain slice.
Journal ArticleDOI
Phylotranscriptomic analysis of the origin and early diversification of land plants
Norman J. Wickett,Siavash Mirarab,Nam Nguyen,Tandy Warnow,Eric J. Carpenter,Naim Matasci,Saravanaraj Ayyampalayam,Michael S. Barker,J. Gordon Burleigh,Matthew A. Gitzendanner,Brad R. Ruhfel,Brad R. Ruhfel,Eric K. Wafula,Joshua P. Der,Sean W. Graham,Sarah Mathews,Michael Melkonian,Douglas E. Soltis,Douglas E. Soltis,Pamela S. Soltis,Pamela S. Soltis,Nicholas W. Miles,Carl J. Rothfels,Carl J. Rothfels,Lisa Pokorny,Lisa Pokorny,A. Jonathan Shaw,Lisa DeGironimo,Dennis W. Stevenson,Barbara Surek,Juan Carlos Villarreal,Béatrice Roure,Hervé Philippe,Hervé Philippe,Claude W. dePamphilis,Tao Chen,Michael K. Deyholos,Regina S. Baucom,Toni M. Kutchan,Megan M. Augustin,Jun Wang,Yong Zhang,Zhijian Tian,Zhixiang Yan,Xiaolei Wu,Xiao Sun,Gane Ka-Shu Wong,Jim Leebens-Mack +47 more
TL;DR: Strong and robust support is found for a sister-group relationship between land plants and one group of streptophyte green algae, the Zygnematophyceae, and suggests that phylogenetic hypotheses used to understand the evolution of fundamental plant traits should be reevaluated.
Journal ArticleDOI
All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins
Daniel Hochbaum,Yongxin Zhao,Samouil L. Farhi,Nathan C. Klapoetke,Christopher A. Werley,Vikrant Kapoor,Peng Zou,Joel M. Kralj,Dougal Maclaurin,Niklas Smedemark-Margulies,Jessica L. Saulnier,Gabriella L. Boulting,Christoph Straub,Yong Ku Cho,Michael Melkonian,Gane Ka-Shu Wong,D. Jed Harrison,Venkatesh N. Murthy,Bernardo L. Sabatini,Edward S. Boyden,Robert E. Campbell,Adam E. Cohen +21 more
TL;DR: In this article, a coexpression vector, Optopatch, enabled cross-talk-free genetically targeted all-optical electrophysiology without the use of conventional electrodes.
Journal ArticleDOI
Data access for the 1,000 Plants (1KP) project.
Naim Matasci,Ling-Hong Hung,Zhixiang Yan,Eric J. Carpenter,Norman J. Wickett,Siavash Mirarab,Nam Nguyen,Tandy Warnow,Saravanaraj Ayyampalayam,Michael S. Barker,J. G. Burleigh,Matthew A. Gitzendanner,Eric K. Wafula,Joshua P. Der,Claude W. dePamphilis,Béatrice Roure,Hervé Philippe,Hervé Philippe,Brad R. Ruhfel,Brad R. Ruhfel,Nicholas W. Miles,Sean W. Graham,Sarah Mathews,Barbara Surek,Michael Melkonian,Douglas E. Soltis,Pamela S. Soltis,Carl J. Rothfels,Carl J. Rothfels,Lisa Pokorny,Lisa Pokorny,Jonathan Shaw,Lisa DeGironimo,Dennis W. Stevenson,Juan Carlos Villarreal,Tao Chen,Toni M. Kutchan,Megan Rolf,Regina S. Baucom,Michael K. Deyholos,Ram Samudrala,Zhijian Tian,Xiaolei Wu,Xiao Sun,Yong Zhang,Jun Wang,Jim Leebens-Mack,Gane Ka-Shu Wong,Gane Ka-Shu Wong +48 more
TL;DR: How to access the data used in a phylogenomics analysis of the first 85 species, and how to visualize the gene and species trees of the 1KP project.