N
Naohiko Seki
Researcher at Chiba University
Publications - 391
Citations - 20245
Naohiko Seki is an academic researcher from Chiba University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 74, co-authored 381 publications receiving 18648 citations. Previous affiliations of Naohiko Seki include Toho University & National Institute of Radiological Sciences.
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Journal ArticleDOI
Differential expression of the L-plastin gene in human colorectal cancer progression and metastasis.
Motoyuki Otsuka,Masaki Kato,Tsutomu Yoshikawa,Hua Chen,Eric J. Brown,Yasuhiko Masuho,Masao Omata,Naohiko Seki +7 more
TL;DR: The results suggest that the L-plastin gene is a potential metastatic marker and combining cDNA microarrays and tissue arrays, as shown here, is thought to facilitate the rapid characterization of candidate biomarkers.
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Tumour-suppressive microRNA-144-5p directly targets CCNE1 / 2 as potential prognostic markers in bladder cancer
Ryosuke Matsushita,Naohiko Seki,Takeshi Chiyomaru,Satoru Inoguchi,Tomoaki Ishihara,Yusuke Goto,Rika Nishikawa,Hiroko Mataki,S. Tatarano,Toshihiko Itesako,Masayuki Nakagawa,Hideki Enokida +11 more
TL;DR: Gain-of-function studies showed that miR-144-5p significantly inhibited cell proliferation by BC cells and might be good prognostic markers for survival of BC patients.
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The tumor-suppressive microRNA-143/145 cluster inhibits cell migration and invasion by targeting GOLM1 in prostate cancer.
Satoko Kojima,Hideki Enokida,Hirofumi Yoshino,Toshihiko Itesako,Takeshi Chiyomaru,Takashi Kinoshita,Miki Fuse,Rika Nishikawa,Yusuke Goto,Yukio Naya,Masayuki Nakagawa,Naohiko Seki +11 more
TL;DR: The data on target genes regulated by the tumor-suppressive miR-143/145 cluster provide new insights into the potential mechanisms of PCa oncogenesis and metastasis.
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Tumor suppressive microRNA-218 inhibits cancer cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma
Takashi Kinoshita,Toyoyuki Hanazawa,Nijiro Nohata,Naoko Kikkawa,Hideki Enokida,Hirofumi Yoshino,Takeshi Yamasaki,Hideo Hidaka,Masayuki Nakagawa,Yoshitaka Okamoto,Naohiko Seki +10 more
TL;DR: Analysis data showed that tumor suppressive miR-218 contributes to cancer cell migration and invasion through regulating focal adhesion pathway, especially laminin-332, which is an important and biologically active part of the basal lamina.
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MicroRNA-218 Inhibits Cell Migration and Invasion in Renal Cell Carcinoma through Targeting Caveolin-2 Involved in Focal Adhesion Pathway
Takeshi Yamasaki,Naohiko Seki,Hirofumi Yoshino,Toshihiko Itesako,Hideo Hidaka,Yasutoshi Yamada,Shuichi Tatarano,Tomokazu Yonezawa,Takashi Kinoshita,Masayuki Nakagawa,Hideki Enokida +10 more
TL;DR: Tumor suppressive microRNA mediated cancer pathways and responsible genes provide new insights into the potential mechanisms of renal cell carcinoma oncogenesis and metastasis.