N
Naohiko Seki
Researcher at Chiba University
Publications - 391
Citations - 20245
Naohiko Seki is an academic researcher from Chiba University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 74, co-authored 381 publications receiving 18648 citations. Previous affiliations of Naohiko Seki include Toho University & National Institute of Radiological Sciences.
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Journal ArticleDOI
Molecular Pathogenesis of Gene Regulation by the miR-150 Duplex: miR-150-3p Regulates TNS4 in Lung Adenocarcinoma.
Shunsuke Misono,Naohiko Seki,Keiko Mizuno,Yasutaka Yamada,Akifumi Uchida,Hiroki Sanada,Shogo Moriya,Naoko Kikkawa,Tomohiro Kumamoto,Takayuki Suetsugu,Hiromasa Inoue +10 more
TL;DR: The approach (discovery of anti-tumor miRNAs and their target RNAs for LUAD) will contribute to the elucidation of molecular networks involved in the malignant transformation of LUAD.
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Laser-captured microdissection-microarray analysis of the genes involved in endometrial carcinogenesis: stepwise up-regulation of lipocalin2 expression in normal and neoplastic endometria and its functional relevance.
Tsutomu Miyamoto,Hiroyasu Kashima,Akihisa Suzuki,Norihiko Kikuchi,Ikuo Konishi,Naohiko Seki,Tanri Shiozawa +6 more
TL;DR: The expression of lipocalin2 increased with the endometrial carcinogenesis, and accumulation of the protein conferred biological aggressiveness to endometial carcinoma cells, suggesting lipocal in2 to be a novel target in the treatment of endometrian carcinoma.
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Structure, expression profile and chromosomal location of an isolog of DNA-PKcs interacting protein (KIP) gene.
Naohiko Seki,Astushi Hattori,Akiko Hayashi,Sumie Kozuma,Miki Ohira,Tada-aki Hori,Toshiyuki Saito +6 more
TL;DR: A novel DNA-PKcs interacting protein, KIP (kinase interacting protein), was recently isolated using a two-hybrid analysis which showed a significant homology to calcineurin B and RT-PCR analysis showed that the messenger RNA was ubiquitously expressed in various human tissues.
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Real‐Time GFP Intravital Imaging of the Differences in Cellular and Angiogenic Behavior of Subcutaneous and Orthotopic Nude‐Mouse Models of Human PC‐3 Prostate Cancer
Yong Zhang,Makoto Toneri,Huaiyu Ma,Zhijian Yang,Michael Bouvet,Yusuke Goto,Naohiko Seki,Robert M. Hoffman +7 more
TL;DR: These results explain why orthotopic tumors mimimc clinical metastatic tumors in nude mice and why subcutaneous tumors do not.
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Expression profiling of liver cell lines expressing entire or parts of hepatitis C virus open reading frame.
Hideki Aizaki,Takashi Harada,Motoyuki Otsuka,Naohiko Seki,Mami Matsuda,Yue Wei Li,Hayato Kawakami,Yoshiharu Matsuura,Tatsuo Miyamura,Tetsuro Suzuki +9 more
TL;DR: Functional genomic approaches comparing expression among the different cell lines expressing parts of the HCV genome may promote the understanding of the molecular basis of pathogenicity of HCV infection.