N
Naohiko Seki
Researcher at Chiba University
Publications - 391
Citations - 20245
Naohiko Seki is an academic researcher from Chiba University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 74, co-authored 381 publications receiving 18648 citations. Previous affiliations of Naohiko Seki include Toho University & National Institute of Radiological Sciences.
Papers
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Journal ArticleDOI
Identification of Tumor-Suppressive miR-30e-3p Targets: Involvement of SERPINE1 in the Molecular Pathogenesis of Head and Neck Squamous Cell Carcinoma
C. Minemura,Shunichi Asai,Ayaka Koma,Ikuko Kase-Kato,Nozomi Tanaka,Naoko Kikkawa,Atsushi Kasamatsu,Hidetaka Yokoe,Toyoyuki Hanazawa,Katsuhiro Uzawa,Naohiko Seki +10 more
TL;DR: This study addressed target genes controlled by miR-30e-3p that were closely associated with the molecular pathogenesis of head and neck squamous cell carcinoma (HNSCC) and found that SERPINE1 was found to be an independent prognostic factor for patient survival.
Journal ArticleDOI
1270 micrornas detection in urine as diagnostic markers and predictors of recurrence of non-muscle invasive bladder cancer
Hideki Enokida,Yasutoshi Yamada,Hirofumi Yoshino,Shuichi Tatarano,Hideo Hidaka,Takeshi Yamasaki,Takeshi Chiyomaru,Satoko Kojima,Naohiko Seki,Masayuki Nakagawa +9 more
TL;DR: The data suggest that detection ofmiR-96 and miR-183 may serve as potential biomarkers for BC diagnosis as well as prediction for tumor recurrence of non-muscle invasive BC.
Patent
Heart20049410 polypeptides and methods of making the same
Takao Isogai,Tomoyasu Sugiyama,Tetsuji Otsuki,Ai Wakamatsu,Hiroyuki Sato,Shizuko Ishii,Jun-Ichi Yamamoto,Yuuko Isono,Yuri Hio,Kaoru Otsuka,Keiichi Nagai,Ryotaro Irie,Ichiro Tamechika,Naohiko Seki,Tsutomu Yoshikawa,Motoyuki Otsuka,Kenji Nagahari,Yasuhiko Masuho +17 more
TL;DR: In this paper, the full-length nucleotide sequences of the cDNA and amino acid sequences encoded by the nucleotide sequence have been determined, and they provide information useful for analyzing the functions of the polypeptide.
Patent
FULL-LENGTH cDNA AND POLYPEPTIDES
Takao Isogai,Tomoyasu Sugiyama,Tetsuji Otsuki,Ai Wakamatsu,Hiroyuki Sato,Shizuko Ishii,Jun-Ichi Yamamoto,Yuuko Isono,Yuri Hio,Kaoru Otsuka,Keiichi Nagai,Ryotaro Irie,Ichiro Tamechika,Naohiko Seki,Tsutomu Yoshikawa,Motoyuki Otsuka,Kenji Nagahari,Yasuhiko Masuho +17 more
Abstract: cDNA derived from human have been isolated. The full-length nucleotide sequences of the cDNA and amino acid sequences encoded by the nucleotide sequences have been determined. Because the cDNA of the present invention are full-length and contain the translation start site, they provide information useful for analyzing the functions of the polypeptide.
Proceedings ArticleDOI
Abstract 132:miR-133aas a tumor suppressive microRNA targeting multiple oncogenes in head neck squamous cell carcinoma
Nijiro Nohata,Toyoyuki Hanazawa,Naoko Kikkawa,Muradil Mutallip,Miki Fuse,Takeshi Chiyomaru,Kazumori Kawakami,Hideki Enokida,Masayuki Nakagawa,Yoshitaka Okamato,Naohiko Seki +10 more
TL;DR: Tumor suppressive miR-133a and its target oncogenes may provide new insights into the mechanisms in cancer and have therapeutic implications and may be exploited for future HNSCC treatments.