N
Naohiko Seki
Researcher at Chiba University
Publications - 391
Citations - 20245
Naohiko Seki is an academic researcher from Chiba University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 74, co-authored 381 publications receiving 18648 citations. Previous affiliations of Naohiko Seki include Toho University & National Institute of Radiological Sciences.
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Isolation and chromosomal mapping of a novel human gene showing homology to Na+/PO4 cotransporter.
TL;DR: A cDNA clone which shows a significant similarity with the renal Na+/phosphate cotransporter (NPT) from a human intestine mucosa cDNA library is isolated and may code for intestinal type NPT or closely related proteins.
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CpG hypermethylation of cellular retinol-binding protein 1 contributes to cell proliferation and migration in bladder cancer
Kazuki Toki,Hideki Enokida,Kazumori Kawakami,Takeshi Chiyomaru,Shuichi Tatarano,Hirofumi Yoshino,Yousuke Uchida,Kazuya Kawahara,Kenryu Nishiyama,Naohiko Seki,Masayuki Nakagawa +10 more
TL;DR: It is demonstrated for the first time that the CRBP1 gene could have a tumor suppressive function in BC and the aberrant CpG hypermethylation of the CR BP1 gene promoter could be involved in the development of BC.
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Two-peaked Synchronization in Day/Night Expression Rhythms of the Fibrinogen Gene Cluster in the Mouse Liver *
Eiko Sakao,Akinori Ishihara,Kazumasa Horikawa,Masashi Akiyama,Makoto Arai,Masaki Kato,Naohiko Seki,Kohji Fukunaga,Atsuko Shimizu-Yabe,Katsuro Iwase,Satoko Ohtsuka,Takeyuki Sato,Yoichi Kohno,Shigenobu Shibata,Masaki Takiguchi +14 more
TL;DR: The fibrinogen gene locus provides a unique system for the study of two-peaked day/night rhythms of gene expression in a synchronized form and a number of sequence elements resembling circadian transcription factor-binding sites were found.
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NF-kappaB and ERK-signaling pathways contribute to the gene expression induced by cag PAI-positive-Helicobacter pylori infection.
Wataru Shibata,Yoshihiro Hirata,Haruhiko Yoshida,Motoyuki Otsuka,Yujin Hoshida,Keiji Ogura,Shin Maeda,Tomoya Ohmae,Ayako Yanai,Yuzo Mitsuno,Naohiko Seki,Takao Kawabe,Masao Omata +12 more
TL;DR: NF-kB and ERK-signaling pathways contribute to the gene expression induced by cag PAI-positive-Helicobacter pylori infection.
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Replisome genes regulation by antitumor miR‐101‐5p in clear cell renal cell carcinoma
Yasutaka Yamada,Nijiro Nohata,Akifumi Uchida,Mayuko Kato,Takayuki Arai,Shogo Moriya,Keiko Mizuno,Satoko Kojima,Kazuto Yamazaki,Yukio Naya,Tomohiko Ichikawa,Naohiko Seki +11 more
TL;DR: The antitumor miR‐101‐5p/DONSON axis and its modulated replisome genes might be a novel diagnostic and therapeutic target for ccRCC.