Naohiko Seki

TL;DR: Results provide additional evidence that the mouse 11B region displays conserved linkage homology with the rat 10q22 region, whereas in the case of RNF16, this homology is only conserved among rodents, distinct from the 1q42 region of the human genome.

TL;DR: The overall frequency of distamycin A-inducible fragile sites in azoospermia patients appeared to be higher than those reported for Japanese healthy subjects and cancer patients, however, no significant relation among fragile sites, clinical and histological findings has been detected so far.

TL;DR: A subtraction procedure was developed for identification and isolation of a human gene transcribed in mouse transformant cells and recovered the human purH gene from a mice transformant cell line, which was originally established by functional complementation using the human metaphase chromosome-mediated gene transfer technique.

TL;DR: The results suggest that functional differences between tissues are probably related to their divergent gene expression profiles, and form a basis for understanding the molecular mechanisms underlying tissue-specific pathogenesis that are expressed in different organs.

TL;DR: In this paper, the major AT loci, AT-A and AT-C, are shown to be closely linked at chromosome Ilq22-q23.1 and include the entire region of the major Ataxia telangiectasia (AT) between D11S1819 and D11 S1818.