N
Naohiko Seki
Researcher at Chiba University
Publications - 391
Citations - 20245
Naohiko Seki is an academic researcher from Chiba University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 74, co-authored 381 publications receiving 18648 citations. Previous affiliations of Naohiko Seki include Toho University & National Institute of Radiological Sciences.
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Journal ArticleDOI
cDNA cloning, expression profile, and genomic structure of human and mouse RNF10/Rnf 10 genes, encoding a novel RING finger protein.
TL;DR: Comparison of the RNF10 and KIAA0262 proteins revealed that both were transcribed from the same gene and that the longer R NF10 ORF would be the authentic form, supported by comparative chromosome mapping.
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The genomic analysis of human DAN gene.
Toshinori Ozaki,Hideki Enomoto,Yohko Nakamura,Kazuhiro Kondo,Naohiko Seki,Miki Ohira,Nobuo Nomura,Misao Ohki,Akira Nakagawara,Shigeru Sakiyama +9 more
TL;DR: Genomic Southern experiments demonstrated that the allelic loss of DAN gene might occur in neuroblastoma, and there exist two dinucleotide repeats, ( CA)7 and (CA)8, in the first intron of D AN gene, raising the possibility to distinguish two alleles of DANA gene in some of the cancer cells.
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A novel human gene whose product shares significant homology with the bovine brain-specific protein p25 on chromosome 5p15.3.
Naohiko Seki,Atsushi Hattori,Sumio Sugano,Yutaka Suzuki,Akira Nakagawara,Masaaki Muramatsu,Tada-aki Hori,Toshiyuki Saito +7 more
TL;DR: The sequence features and chromosomal location of a novel human gene which shares significant homology with the bovine brain-specific protein p25.3 region of chromosome 5 is reported on.
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Chromosome Mapping of Human (ZNF179), Mouse, and Rat Genes for Brain Finger Protein (bfp), a Member of the RING Finger Family
Yoichi Matsuda,Satoshi Inoue,Satoshi Inoue,Naohiko Seki,Takayuki Hosoi,Akira Orimo,Masami Muramatsu,Tada-aki Hori +7 more
TL;DR: Ch Chromosome mapping of the bfp gene by fluorescence in situ hybridization reveals that human BFP (ZNF179) is located at 17p11.2, mouse Bfp at 11B1, and rat BFP at 10q22.3, providing additional evidence that the mouse 11B region displays conserved linkage homology with the 17p 11.2 region of the human genome and the 10q 22 region ofThe rate genome.
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Regulation of aberrantly expressed SERPINH1 by antitumor miR-148a-5p inhibits cancer cell aggressiveness in gastric cancer.
Kosuke Kawagoe,Masumi Wada,Tetsuya Idichi,Reona Okada,Yasutaka Yamada,Shogo Moriya,Keishi Okubo,Daisuke Matsushita,Takaaki Arigami,Hiroshi Kurahara,Kosei Maemura,Shoji Natsugoe,Naohiko Seki +12 more
TL;DR: The search for miRNA target genes identified a total of 18 oncogenic targets of miR-148a-5p in GC cells and focused on SERPINH1 as a chaperone protein involved in collagen folding in humans for understanding of the molecular pathogenesis of GC.