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Naohiko Seki

Researcher at Chiba University

Publications -  391
Citations -  20245

Naohiko Seki is an academic researcher from Chiba University. The author has contributed to research in topics: microRNA & Cancer. The author has an hindex of 74, co-authored 381 publications receiving 18648 citations. Previous affiliations of Naohiko Seki include Toho University & National Institute of Radiological Sciences.

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cDNA cloning, expression profile, and genomic structure of human and mouse RNF10/Rnf 10 genes, encoding a novel RING finger protein.

TL;DR: Comparison of the RNF10 and KIAA0262 proteins revealed that both were transcribed from the same gene and that the longer R NF10 ORF would be the authentic form, supported by comparative chromosome mapping.
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The genomic analysis of human DAN gene.

TL;DR: Genomic Southern experiments demonstrated that the allelic loss of DAN gene might occur in neuroblastoma, and there exist two dinucleotide repeats, ( CA)7 and (CA)8, in the first intron of D AN gene, raising the possibility to distinguish two alleles of DANA gene in some of the cancer cells.
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A novel human gene whose product shares significant homology with the bovine brain-specific protein p25 on chromosome 5p15.3.

TL;DR: The sequence features and chromosomal location of a novel human gene which shares significant homology with the bovine brain-specific protein p25.3 region of chromosome 5 is reported on.
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Chromosome Mapping of Human (ZNF179), Mouse, and Rat Genes for Brain Finger Protein (bfp), a Member of the RING Finger Family

TL;DR: Ch Chromosome mapping of the bfp gene by fluorescence in situ hybridization reveals that human BFP (ZNF179) is located at 17p11.2, mouse Bfp at 11B1, and rat BFP at 10q22.3, providing additional evidence that the mouse 11B region displays conserved linkage homology with the 17p 11.2 region of the human genome and the 10q 22 region ofThe rate genome.
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Regulation of aberrantly expressed SERPINH1 by antitumor miR-148a-5p inhibits cancer cell aggressiveness in gastric cancer.

TL;DR: The search for miRNA target genes identified a total of 18 oncogenic targets of miR-148a-5p in GC cells and focused on SERPINH1 as a chaperone protein involved in collagen folding in humans for understanding of the molecular pathogenesis of GC.