N
Nicola L. Harris
Researcher at Monash University
Publications - 121
Citations - 10360
Nicola L. Harris is an academic researcher from Monash University. The author has contributed to research in topics: Immune system & Heligmosomoides polygyrus. The author has an hindex of 40, co-authored 110 publications receiving 8780 citations. Previous affiliations of Nicola L. Harris include University of Lausanne & University of Otago.
Papers
More filters
Journal ArticleDOI
Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis
Aurélien Trompette,Eva S. Gollwitzer,Koshika Yadava,Anke Sichelstiel,Norbert Sprenger,Catherine Ngom-Bru,Carine Blanchard,Tobias Junt,Laurent P. Nicod,Nicola L. Harris,Benjamin J. Marsland +10 more
TL;DR: The results show that dietary fermentable fiber and SCFAs can shape the immunological environment in the lung and influence the severity of allergic inflammation.
Journal ArticleDOI
Interactions between commensal intestinal bacteria and the immune system
TL;DR: The developing understanding of the far-reaching effects that the commensal flora have on mucosal and systemic immunity and their relevance to the effects of hygiene on human disease is described.
Journal ArticleDOI
Neuronal regulation of type 2 innate lymphoid cells via neuromedin U
Vânia Cardoso,Julie Chesné,Hélder Ribeiro,Bethania García-Cassani,Tânia Carvalho,Tiffany Bouchery,Kathleen Shah,Nuno L. Barbosa-Morais,Nicola L. Harris,Henrique Veiga-Fernandes +9 more
TL;DR: It is shown that neuromedin U (NMU) in mice is a fast and potent regulator of type 2 innate immunity in the context of a functional neuron–ILC2 unit, and this work reveals that neuron–ilC2 cell units confer immediate tissue protection through coordinated neuroimmune sensory responses.
Journal ArticleDOI
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease.
Karl S. Lang,Mike Recher,Tobias Junt,Alexander A. Navarini,Nicola L. Harris,Stefan Freigang,Bernhard Odermatt,Curdin Conrad,Lars M. Ittner,Stefan Bauer,Sanjiv A. Luther,Satoshi Uematsu,Shizuo Akira,Hans Hengartner,Rolf M. Zinkernagel +14 more
TL;DR: The circumstances under which CD8+ T cells specific for pancreatic beta-islet antigens induce disease in mice expressing lymphocytic choriomeningitis virus as a transgene under the control of the rat insulin promoter are investigated to identify the 'inflammatory status' of the target organ as a separate and limiting factor determining the development of autoimmune disease.
Journal ArticleDOI
Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization
Tina Herbst,Anke Sichelstiel,Corinne Schär,Koshika Yadava,Kurt Bürki,Julia Cahenzli,Kathy D. McCoy,Benjamin J. Marsland,Nicola L. Harris +8 more
TL;DR: In this paper, the authors used a model of allergic airway inflammation in GF mice to ascertain the relevance of commensal bacteria on the development of an allergic response, and found that the total number of infiltrating lymphocytes and eosinophils were elevated in the airways of allergic GF mice compared with control SPF mice.