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Pejman Mohammadi
Researcher at Scripps Research Institute
Publications - 61
Citations - 3859
Pejman Mohammadi is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Gene & Population. The author has an hindex of 22, co-authored 53 publications receiving 2651 citations. Previous affiliations of Pejman Mohammadi include University of Lausanne & University Hospital of Lausanne.
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Journal ArticleDOI
Dynamics of HIV Latency and Reactivation in a Primary CD4+ T Cell Model
Pejman Mohammadi,Julia di Iulio,Miguel Munoz,Raquel Martinez,Istvan Bartha,Matthias Cavassini,Christian W. Thorball,Jacques Fellay,Niko Beerenwinkel,Angela Ciuffi,Amalio Telenti +10 more
TL;DR: It is observed that latently infected CD4+ T cells from HIV-infected individuals failed to produce viral particles upon ex vivo exposure to SAHA (vorinostat), despite effective inhibition of histone deacetylases.
Journal ArticleDOI
TiMEx: A Waiting Time Model for Mutually Exclusive Cancer Alterations
TL;DR: TiMEx as discussed by the authors is a generative probabilistic model for detecting patterns of various degrees of mutual exclusivity across genetic alterations, which can indicate pathways involved in cancer progression.
Journal ArticleDOI
A vast resource of allelic expression data spanning human tissues
Stephane E. Castel,François Aguet,Pejman Mohammadi,Shankara Anand,Kristin G. Ardlie,Stacey Gabriel,Gad Getz,Aaron Graubert,Kane Hadley,Robert E. Handsaker,Katherine H. Huang,Seva Kashin,Xiao Li,Daniel G. MacArthur,Sam Meier,Jared L. Nedzel,Duyen T. Nguyen,Ayellet V. Segrè,Ellen Todres,Brunilda Balliu,Alvaro N. Barbeira,Alexis Battle,Rodrigo Bonazzola,Andrew Brown,Christopher D. Brown,Donald F. Conrad,Daniel J. Cotter,Nancy J. Cox,Sayantan Das,Olivia M. De Goede,Emmanouil T. Dermitzakis,Jonah Einson,Barbara E. Engelhardt,Eleazar Eskin,Tiffany Eulalio,Nicole M. Ferraro,Elise D. Flynn,Laure Fresard,Eric R. Gamazon,Diego Garrido-Martín,Michael J. Gloudemans,Roderic Guigó,Andrew R. Hame,Yuan He,Paul J. Hoffman,Farhad Hormozdiari,Lei Hou,Hae Kyung Im,Brian Jo,Silva Kasela,Manolis Kellis,Sarah Kim-Hellmuth,Alan Kwong,Tuuli Lappalainen,Xin Li,Yanyu Liang,Serghei Mangul,Stephen B. Montgomery,Manuel Muñoz-Aguirre,Daniel Nachun,Andrew B. Nobel,Meritxell Oliva,YoSon Park,Yongjin Park,Princy Parsana,Abhiram Rao,Ferran Reverter,John M. Rouhana,Chiara Sabatti,Ashis Saha,Andrew D. Skol,Matthew Stephens,Barbara E. Stranger,Benjamin J. Strober,Nicole A. Teran,Ana Viñuela,Gao Wang,Xiaoquan Wen,Fred A. Wright,Valentin Wucher,Yuxin Zou,Pedro G. Ferreira,Gen Li,Marta Melé,Esti Yeger-Lotem,Mary Barcus,Debra Bradbury,Tanya Krubit,Jeffrey McLean,Liqun Qi,Karna Robinson,Nancy Roche,Anna M. Smith,Leslie H. Sobin,David Tabor,Anita H. Undale,Jason Bridge,Lori E. Brigham,Barbara A. Foster,Bryan Gillard,Richard Hasz,Marcus Hunter,Christopher Johns,Mark H. Johnson,Ellen Karasik,Gene Kopen,William F. Leinweber,Alisa McDonald,Michael T. Moser,Kevin Myer,Kimberley Ramsey,Brian Roe,Saboor Shad,Jeffrey A. Thomas,Gary Walters,Michael Washington,Joseph Wheeler,Scott D. Jewell,Daniel C. Rohrer,Dana R. Valley,David A. Davis,Deborah C. Mash,Philip A. Branton,Laura Barker,Heather M. Gardiner,Maghboeba Mosavel,Laura A. Siminoff,Paul Flicek,Maximilian Haeussler,Thomas Juettemann,W. James Kent,Christopher Lee,Conner C. Powell,Kate R. Rosenbloom,Magali Ruffier,Dan Sheppard,Kieron Taylor,Stephen J. Trevanion,Daniel R. Zerbino,Nathan S. Abell,Joshua M. Akey,Lin Chen,Kathryn Demanelis,Jennifer A. Doherty,Andrew P. Feinberg,Kasper D. Hansen,Peter Hickey,Farzana Jasmine,Lihua Jiang,Rajinder Kaul,Muhammad G. Kibriya,Jin Billy Li,Qin Li,Shin Lin,Sandra Linder,Brandon L. Pierce,Lindsay F. Rizzardi,Kevin S. Smith,Michael Snyder,John A. Stamatoyannopoulos,Hua Tang,Meng Wang,Latarsha J. Carithers,Ping Guan,Susan E. Koester,A. Roger Little,Helen M. Moore,Concepcion R. Nierras,Abhi Rao,Jimmie B. Vaught,Simona Volpi +170 more
TL;DR: A vast AE resource generated from the GTEx v8 release is presented and the utility of this resource is demonstrated, and an extension of the tool phASER is developed that allows effect sizes of cis -regulatory variants to be estimated using haplotype-level AE data.
Journal ArticleDOI
Promoter-interacting expression quantitative trait loci are enriched for functional genetic variants
Vivek Chandra,Sourya Bhattacharyya,Benjamin J Schmiedel,Ariel Madrigal,Cristian Gonzalez-Colin,Stephanie Fotsing,Austin Crinklaw,Grégory Seumois,Pejman Mohammadi,Mitchell Kronenberg,Mitchell Kronenberg,Bjoern Peters,Bjoern Peters,Ferhat Ay,Ferhat Ay,Pandurangan Vijayanand,Pandurangan Vijayanand,Pandurangan Vijayanand +17 more
TL;DR: In this article, the authors used H3K27ac HiChIP assays to identify functionally important eQTLs and show mechanisms that explain their cell-type restriction.
Journal ArticleDOI
Integrative genomic analyses identify susceptibility genes underlying COVID-19 hospitalization.
Gita A. Pathak,Gita A. Pathak,Kritika Singh,Tyne W Miller-Fleming,Frank R. Wendt,Frank R. Wendt,Nava Ehsan,Kangcheng Hou,Ruth Johnson,Zeyun Lu,Shyamalika Gopalan,Loic Yengo,Pejman Mohammadi,Bogdan Pasaniuc,Renato Polimanti,Renato Polimanti,Lea K. Davis,Nicholas Mancuso +17 more
TL;DR: In this paper, the authors integrated a genome-wide association study of COVID-19 hospitalization with mRNA expression, splicing, and protein levels (n = 18,502).