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Philipp Zickler

Researcher at Augsburg College

Publications -  22
Citations -  867

Philipp Zickler is an academic researcher from Augsburg College. The author has contributed to research in topics: Stroke & Medicine. The author has an hindex of 10, co-authored 18 publications receiving 750 citations. Previous affiliations of Philipp Zickler include University of Freiburg & National Institutes of Health.

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Increased thalamic neurodegeneration following ischaemic cortical stroke in osteopontin-deficient mice.

TL;DR: In this article, the role of osteopontin (OPN) in ischaemic brain injury using OPN knockout (KO) mice in models of cortical stroke was addressed.
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Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial.

Gil I. Wolfe, +324 more
- 01 Mar 2019 - 
TL;DR: At 5 years, thymectomy plus prednisone continues to confer benefits in patients with generalised non-thymomatous myasthenia gravis compared withprednisone alone, and the primary endpoints of the extension phase were the time-weighted means of the QMG score and alternate-day Prednisone dose from month 0 to month 60.
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Many multipotential gene-marked progenitor or stem cell clones contribute to hematopoiesis in nonhuman primates.

TL;DR: The results support the concept that hematopoiesis in large animals is polyclonal and that individual multipotential stem or progenitor cells can contribute to hematopoliesis for prolonged periods.
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Hematopoietic stem cell transplantation prevents diabetes in NOD mice but does not contribute to significant islet cell regeneration once disease is established.

TL;DR: Allogeneic bone marrow transplantation prevents autoimmune diabetes and tolerizes the recipient to donor islet grants, even in diabetic animals, yet the capacity of bone marrow derived cells to differentiate into functional islet cells, at least without additional manipulation, is limited in this model.