R
Rik Vandenberghe
Researcher at Allen Institute for Brain Science
Publications - 430
Citations - 26622
Rik Vandenberghe is an academic researcher from Allen Institute for Brain Science. The author has contributed to research in topics: Frontotemporal dementia & Medicine. The author has an hindex of 69, co-authored 355 publications receiving 21180 citations. Previous affiliations of Rik Vandenberghe include Northwestern University & Katholieke Universiteit Leuven.
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Journal ArticleDOI
Moral processing deficit in behavioral variant frontotemporal dementia is associated with facial emotion recognition and brain changes in default mode and salience network areas.
Jan Van den Stock,Daphne Stam,François-Laurent De Winter,Dante Mantini,Dante Mantini,Dante Mantini,Benedikt Szmrecsanyi,Koen Van Laere,Rik Vandenberghe,Mathieu Vandenbulcke +9 more
TL;DR: Behavioral variant frontotemporal dementia (bvFTD) is associated with abnormal emotion recognition and moral processing.
Journal ArticleDOI
Cholinergic depletion and basal forebrain volume in primary progressive aphasia
Jolien Schaeverbeke,Charlotte Evenepoel,Rose Bruffaerts,Koen Van Laere,Guy Bormans,Eva Dries,Thomas Tousseyn,Natalie Nelissen,Ronald Peeters,Mathieu Vandenbulcke,Patrick Dupont,Rik Vandenberghe +11 more
TL;DR: To conclude, in the authors' sample of PPA patients, LV but not SV was associated with cholinergic depletion, and BF atrophy in PPA does not imply cholinergy depletion.
Journal ArticleDOI
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer’s disease
Pieter Jelle Visser,Lianne M. Reus,Johan Gobom,Iris E. Jansen,Ellen Dicks,S. J. van der Lee,Magda Tsolaki,Frans R.J. Verhey,Julius Popp,Pablo Martinez-Lage,Rik Vandenberghe,Alberto Lleó,José Luis Molinuevo,Sebastiaan Engelborghs,Yvonne Freund-Levi,Lutz Froelich,Kristel Sleegers,Valerija Dobricic,Simon Lovestone,Johannes Streffer,Stephanie J.B. Vos,Isabelle Bos,August B. Smit,Kaj Blennow,Philip Scheltens,Charlotte E. Teunissen,Lars Bertram,Henrik Zetterberg,Betty M. Tijms +28 more
TL;DR: This article found that individuals with increased t-tau had increased CSF concentrations of over 400 proteins enriched for neuronal plasticity processes and showed increased concentrations of proteins indicative of blood-brain barrier and blood-CSF barrier dysfunction, relative to controls.
Journal ArticleDOI
Baseline Cognition Is the Best Predictor of 4-year Cognitive Change in Cognitively Intact Older Adults
Jolien Schaeverbeke,Silvy Gabel,Karen Meersmans,Emma Susanne Luckett,Steffi De Meyer,Steffi De Meyer,Katarzyna Adamczuk,Natalie Nelissen,Valerie Goovaerts,Ahmed Radwan,Stefan Sunaert,Patrick Dupont,Koen Van Laere,Rik Vandenberghe,Rik Vandenberghe +14 more
TL;DR: In this paper, the relative weight of cognitive, genetic, structural and amyloid brain imaging variables for predicting cognitive change over a 4-year time course was examined in cognitively intact older adults.
Journal ArticleDOI
Clinical value of cerebrospinal fluid neurofilament light chain in semantic dementia
Lieke H.H. Meeter,Rebecca M. E. Steketee,Dina Salkovic,Maartje E Vos,Murray Grossman,Corey T. McMillan,David J. Irwin,Adam L. Boxer,Julio C. Rojas,Nicholas T. Olney,Anna Karydas,Bruce L. Miller,Yolande A.L. Pijnenburg,Frederik Barkhof,Raquel Sánchez-Valle,Albert Lladó,Sergi Borrego-Écija,Janine Diehl-Schmid,Timo Grimmer,Oliver Goldhardt,Alexander Santillo,Oskar Hansson,Susanne Vestberg,Barbara Borroni,Alessandro Padovani,Daniela Galimberti,Elio Scarpini,Jonathan D. Rohrer,Ione O.C. Woollacott,Matthis Synofzik,Carlo Wilke,Alexandre de Mendonça,Rik Vandenberghe,Luisa Benussi,Roberta Ghidoni,Giuliano Binetti,Wiro J. Niessen,Wiro J. Niessen,Janne M. Papma,Harro Seelaar,Lize C. Jiskoot,Frank Jan de Jong,Laura Donker Kaat,Laura Donker Kaat,Marta Del Campo,Charlotte E. Teunissen,Esther E. Bron,Esther van den Berg,John C. van Swieten +48 more
TL;DR: Cerebrospinal fluid NfL is a promising biomarker in the diagnostic process of SD, although it has limited cross-sectional monitoring or prognostic abilities.