Rik Vandenberghe

TL;DR: These single-case lesion data establish the critical role of the posterior and the middle IPS segment in spatially selective attention and are in line with a vast amount of functional imaging evidence in the intact brain pointing to the prominent role ofThe intraparietal sulcus in spatial attention, along with inferior parietal cortex under specific circumstances.

TL;DR: In this article, a large genetic association study was performed by merging all available case-control datasets and by-proxy study results (discovery n = 409,435 and validation size n = 58,190).

TL;DR: The ability to identify individuals at increased genetic risk for Alzheimer's disease (AD) may streamline biomarker and drug trials and aid clinical and personal decision making.

TL;DR: Raised GFAP concentrations appear to be unique to GRN-related FTD, with levels potentially increasing just prior to symptom onset, suggesting that GFAP may be an important marker of proximity to onset, and helpful for forthcoming therapeutic prevention trials.

TL;DR: This work will incorporate amyloid imaging into a multidimensional model of Alzheimer's disease, including a tentative algorithm for when it may be useful in a memory clinic environment and gaps in evidence-based knowledge of the added value will be identified.