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Shigehiko Suzuki
Researcher at Kyoto University
Publications - 185
Citations - 6020
Shigehiko Suzuki is an academic researcher from Kyoto University. The author has contributed to research in topics: Basic fibroblast growth factor & Dermis. The author has an hindex of 37, co-authored 183 publications receiving 5383 citations. Previous affiliations of Shigehiko Suzuki include Saga Group.
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Journal ArticleDOI
Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness
Takayuki Kondo,Masashi Asai,Masashi Asai,Kayoko Tsukita,Yumiko Kutoku,Yutaka Ohsawa,Yoshihide Sunada,Keiko Imamura,Naohiro Egawa,Naoki Yahata,Keisuke Okita,Kazutoshi Takahashi,Isao Asaka,Takashi Aoi,Akira Watanabe,Kaori Watanabe,Chie Kadoya,Rie Nakano,Dai Watanabe,Kei Maruyama,Osamu Hori,Satoshi Hibino,Tominari Choshi,Tatsutoshi Nakahata,Hiroyuki Hioki,Takeshi Kaneko,Motoko Naitoh,Katsuhiro Yoshikawa,Satoko Yamawaki,Shigehiko Suzuki,Ryuji Hata,Shu-ichi Ueno,Tsuneyoshi Seki,Kazuhiro Kobayashi,Tatsushi Toda,Kazuma Murakami,Kazuhiro Irie,William L. Klein,Hiroshi Mori,Takashi Asada,Ryosuke Takahashi,Nobuhisa Iwata,Shinya Yamanaka,Haruhisa Inoue +43 more
TL;DR: Differential manifestation of ER stress and DHA responsiveness may help explain variable clinical results obtained with the use of DHA treatment and suggests that DHA may in fact be effective for a subset of patients.
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Drug screening for ALS using patient-specific induced pluripotent stem cells.
Naohiro Egawa,Shiho Kitaoka,Kayoko Tsukita,Motoko Naitoh,Kazutoshi Takahashi,Takuya Yamamoto,Fumihiko Adachi,Takayuki Kondo,Keisuke Okita,Isao Asaka,Takashi Aoi,Akira Watanabe,Yasuhiro Yamada,Asuka Morizane,Jun Takahashi,Takashi Ayaki,Hidefumi Ito,Katsuhiro Yoshikawa,Satoko Yamawaki,Shigehiko Suzuki,Dai Watanabe,Hiroyuki Hioki,Takeshi Kaneko,Kouki Makioka,Koichi Okamoto,Hiroshi Takuma,Akira Tamaoka,Kazuko Hasegawa,Takashi Nonaka,Masato Hasegawa,Akihiro Kawata,Minoru Yoshida,Tatsutoshi Nakahata,Ryosuke Takahashi,Maria C. Marchetto,Fred H. Gage,Shinya Yamanaka,Haruhisa Inoue +37 more
TL;DR: The new work provides an encouraging step toward using motor neurons generated from iPSCs derived from ALS patients to learn more about what triggers the death of motor neurons in this disease and to identify new candidate drugs that may be able to slow or reverse the devastating loss ofMotor neurons.
Journal ArticleDOI
Accelerated tissue regeneration through incorporation of basic fibroblast growth factor-impregnated gelatin microspheres into artificial dermis
TL;DR: It is concluded that the gelatin microsphere is a promising tool to accelerate bFGF-induced tissue regeneration in artificial dermis.
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Long-term follow-up study of artificial dermis composed of outer silicone layer and inner collagen sponge.
Shigehiko Suzuki,Katsuya Kawai,Faramartz Ashoori,Naoki Morimoto,Yoshihiko Nishimura,Yoshito Ikada +5 more
TL;DR: The long-term postoperative appearance of the STSG site was good though a very thin STSG is used; scarring of the donor site was minimal and it was possible to take repeated skin grafts from the same donor site.
Journal ArticleDOI
Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5.
Kazuo Noda,Branka Dabovic,Kyoko Takagi,Tadashi Inoue,Masahito Horiguchi,Maretoshi Hirai,Yusuke Fujikawa,Tomoya O. Akama,Kenji Kusumoto,Lior Zilberberg,Lynn Y. Sakai,Katri Koli,Motoko Naitoh,Harald von Melchner,Shigehiko Suzuki,Daniel B. Rifkin,Tomoyuki Nakamura +16 more
TL;DR: It is shown that latent TGF-β binding protein 4 (LTBP-4) potentiates formation of elastic fibers through interacting with fibulin-5, a tropoelastin-binding protein necessary for elastogenesis.