S
Stanley Nattel
Researcher at Montreal Heart Institute
Publications - 802
Citations - 72437
Stanley Nattel is an academic researcher from Montreal Heart Institute. The author has contributed to research in topics: Atrial fibrillation & Heart failure. The author has an hindex of 132, co-authored 778 publications receiving 65700 citations. Previous affiliations of Stanley Nattel include Mayo Clinic & Brigham and Women's Hospital.
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Journal ArticleDOI
Transmural expression of transient outward potassium current subunits in normal and failing canine and human hearts
Stephen Zicha,Stephen Zicha,Ling Xiao,Ling Xiao,Sara Stafford,Tae Joon Cha,Wei Han,András Varró,Stanley Nattel,Stanley Nattel +9 more
TL;DR: It is concluded that both Kv 4.3 and KChIP2 may contribute to epicardial–endocardial gradients in Ito, and that Ito down‐regulation in human and canine CHF appears due primarily to changes in Kv4.3.
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Lone Atrial Fibrillation Does it Exist
D. George Wyse,Isabelle C. Van Gelder,Patrick T. Ellinor,Alan S. Go,Jonathan M. Kalman,Sanjiv M. Narayan,Stanley Nattel,Ulrich Schotten,Michiel Rienstra +8 more
TL;DR: There are no apparently unique mechanisms for AF in patients categorized as having lone AF and the term "lone AF" is not invariably useful in making treatment decisions, and other tools for doing so have been more thoroughly and carefully validated.
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Protein Kinase C Activates ATP-Sensitive K+ Current in Human and Rabbit Ventricular Myocytes
TL;DR: It is concluded that PKC activates I(KATP) in rabbit and human ventricular myocytes by reducing channel sensitivity to intracellular ATP and has potentially important implications for understanding the mechanisms of ischemic preconditioning.
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Transient outward and delayed rectifier currents in canine atrium: properties and role of isolation methods
TL;DR: It is concluded that Ito1, Ito2, and both components of IK are present in dog atrium, IK is much more sensitive to the isolation method than Ito3, and the properties of two important repolarizing currents (Ito1 and IK) previously described in human atrium are similar to those inDog atrium.
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Targeted ablation of ILK from the murine heart results in dilated cardiomyopathy and spontaneous heart failure
Donald E. White,Pierre Coutu,Yanfen Shi,Jean-Claude Tardif,Stanley Nattel,René St.-Arnaud,Shoukat Dedhar,William J. Muller +7 more
TL;DR: It is shown that targeted ablation of the integrin-linked kinase (ILK) expression results in spontaneous cardiomyopathy and heart failure by 6 wk of age, suggesting that ILK plays a central role in protecting the mammalian heart against cardiomeopathy and failure.