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Stanley Nattel
Researcher at Montreal Heart Institute
Publications - 802
Citations - 72437
Stanley Nattel is an academic researcher from Montreal Heart Institute. The author has contributed to research in topics: Atrial fibrillation & Heart failure. The author has an hindex of 132, co-authored 778 publications receiving 65700 citations. Previous affiliations of Stanley Nattel include Mayo Clinic & Brigham and Women's Hospital.
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Journal ArticleDOI
Ionic determinants of functional reentry in a 2-D model of human atrial cells during simulated chronic atrial fibrillation.
Sandeep V. Pandit,Omer Berenfeld,Justus M.B. Anumonwo,Roman M. Zaritski,James Kneller,Stanley Nattel,José Jalife +6 more
TL;DR: Simulation results provide novel insights into the ionic bases of a sustained rotor in a 2-D chronic AF substrate and eliminate random tip meander and wavebreak in rotor termination.
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Rapid and slow components of delayed rectifier current in human atrial myocytes
TL;DR: IK in human atrium shows kinetically distinguishable rapid and slow components that correspond to E-4031 sensitive and resistant currents, which have important potential implications for understanding the mechanisms of human atrial repolarisation and its regulation by the autonomic nervous system and antiarrhythmic drugs.
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Differential Behaviors of Atrial Versus Ventricular Fibroblasts A Potential Role for Platelet-Derived Growth Factor in Atrial-Ventricular Remodeling Differences
TL;DR: Atrial fibroblasts behave differently than ventricular fibro Blasts over a range of in vitro and in vivo paradigms, with atrial Fibroblast showing enhanced reactivity that may explain greater atrial fibrotic responses.
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Enalapril effects on atrial remodeling and atrial fibrillation in experimental congestive heart failure.
TL;DR: A role for the renin-angiotensin system in arrhythmogenic atrial structural remodeling in CHF is indicated and ACE inhibition attenuates CHF-induced atrial fibrosis and remodeling and reduces associated AF promotion.
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Human atrial ion channel and transporter subunit gene-expression remodeling associated with valvular heart disease and atrial fibrillation.
Nathalie Gaborit,Marja Steenman,Guillaume Lamirault,Nolwenn Le Meur,Sabrina Le Bouter,Gilles Lande,Jean J. Leger,Flavien Charpentier,Torsten Christ,Dobromir Dobrev,Denis Escande,Stanley Nattel,Sophie Demolombe +12 more
TL;DR: VHD extensively remodels cardiac ion-channel and transporter expression, and AF alters ion-Channel expression in VHD patients.