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Stanley Nattel
Researcher at Montreal Heart Institute
Publications - 802
Citations - 72437
Stanley Nattel is an academic researcher from Montreal Heart Institute. The author has contributed to research in topics: Atrial fibrillation & Heart failure. The author has an hindex of 132, co-authored 778 publications receiving 65700 citations. Previous affiliations of Stanley Nattel include Mayo Clinic & Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Heat shock proteins as molecular targets for intervention in atrial fibrillation
Bianca J. J. M. Brundel,Lei Ke,Anne-Jan Dijkhuis,Xiao-Yan Qi,Xiao-Yan Qi,Akiko Shiroshita-Takeshita,Stanley Nattel,Stanley Nattel,Robert H. Henning,Harm H. Kampinga +9 more
TL;DR: In this article, heat shock proteins (HSPs) are used to prevent atrial remodelling and attenuate the promotion of atrial fibrillation in both cellular and animal experimental models.
Journal ArticleDOI
Atrial electrophysiology and mechanisms of atrial fibrillation.
TL;DR: The multiple potential mechanisms of atrial fibrillation are considered as contributing to the pathophysiology of the arrhythmia to a different extent in different clinical settings and interacting with each other in a dynamic way at various stages of the natural history in many patients.
Journal ArticleDOI
Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2.
Yun Fang,Gernot Schram,Victor G. Romanenko,Congzhu Shi,Lisa R. Conti,Carol A. Vandenberg,Peter F. Davies,Stanley Nattel,Irena Levitan +8 more
TL;DR: Functional analysis of endothelial inward rectifier K(+) current (I(K)) demonstrated that I(K) current sensitivity to Ba(2+) and pH were consistent with currents determined using Kir 2.2 but not Kir2.3 or dnKir2.4, and unitary conductance distributions showed two prominent peaks corresponding to known unitary Conductance of Kir22.2.
Journal ArticleDOI
Profibrotic, Electrical, and Calcium-Handling Remodeling of the Atria in Heart Failure Patients With and Without Atrial Fibrillation
Cristina E. Molina,Cristina E. Molina,Cristina E. Molina,Issam Abu-Taha,Qiongling Wang,Elena Roselló-Díez,Marcus Kamler,Stanley Nattel,Stanley Nattel,Stanley Nattel,Ursula Ravens,Ursula Ravens,Xander H.T. Wehrens,Leif Hove-Madsen,Jordi Heijman,Dobromir Dobrev +15 more
TL;DR: Novel insights into the molecular substrate for atrial arrhythmias in HF-patients position Ca2+-handling abnormalities as a likely trigger of AF in HF patients, which subsequently produces electrical remodeling that promotes the maintenance of the arrhythmia.
Journal ArticleDOI
Antiarrhythmic drug classifications. A critical appraisal of their history, present status, and clinical relevance.
Stanley Nattel,Stanley Nattel +1 more
TL;DR: A critical analysis of selected aspects of the clinical actions of antiarrhythmic drugs indicates the value of the current classification, as well as some limitations in its ability to separate drugs into distinct groups with characteristic clinical properties.