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Stanley Nattel
Researcher at Montreal Heart Institute
Publications - 802
Citations - 72437
Stanley Nattel is an academic researcher from Montreal Heart Institute. The author has contributed to research in topics: Atrial fibrillation & Heart failure. The author has an hindex of 132, co-authored 778 publications receiving 65700 citations. Previous affiliations of Stanley Nattel include Mayo Clinic & Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
A unified model of atrioventricular nodal conduction predicts dynamic changes in Wenckebach periodicity.
TL;DR: It is concluded that a mathematical model incorporating terms to describe recovery, facilitation, and fatigue accurately predicts a wide range of Wenckebach-type behavior and that complex conduction patterns of the AV node can be fully accounted for by simple functional AV nodal properties.
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Knock-in gain-of-function sodium channel mutation prolongs atrial action potentials and alters atrial vulnerability.
Andreas Blana,Sven Kaese,Lisa Fortmüller,Sandra Laakmann,Dierk Damke,Kelly A. van Bragt,Jens Eckstein,Ilaria Piccini,Uwe Kirchhefer,Stanley Nattel,Günter Breithardt,Peter Carmeliet,Edward Carmeliet,Ulrich Schotten,Sander Verheule,Paulus Kirchhof,Larissa Fabritz +16 more
TL;DR: Murine hearts bearing an LQT3 mutation show abnormalities in atrial electrophysiology and subtle changes in atrian dimension, including an atrial arrhythmogenic phenotype on provocation, and indicate that murine sodium channel LQTS models may be useful for exploring underlying mechanisms.
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Differential alterations of receptor densities of three muscarinic acetylcholine receptor subtypes and current densities of the corresponding K+ channels in canine atria with atrial fibrillation induced by experimental congestive heart failure.
TL;DR: Differential alterations of mAChR subtypes underlie differential alterations of their coupled K+ channels in AF atria and these differential alterations may contribute to atrial remodeling in AF induced in the setting of CHF.
Clinical Research Adenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination (ADVICE): Methods and Rationale
Laurent Macle,Paul Khairy,Atul Verma,Rukshen Weerasooriya,Stephan Willems,Thomas Arentz,Paul Novak,George D. Veenhuyzen,C. Scavee,Allan C. Skanes,Helmut Puererfellner,Yaariv Khaykin,Lena Rivard,Peter G. Guerra,Marc Dubuc,Bernard Thibault,Mario Talajic,Denis Roy,Stanley Nattel +18 more
TL;DR: The ADVICE trial will assess whether a PVI strategy incorporating elimination of dormant conduction unmasked by intravenous adenosine will decrease the rate of recurrent symptomatic AF compared with standard PVI.
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Remodeling of Ca2+-handling by atrial tachycardia: evidence for a role in loss of rate-adaptation
TL;DR: Ca(2+)-handling changes appear to contribute to this clinically significant phenomenon of atrial tachycardia-induced remodeling, and ICR alone does not fully account for loss of APD rate-adaptation with atrial remodeling.