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Stanley Nattel

Researcher at Montreal Heart Institute

Publications -  802
Citations -  72437

Stanley Nattel is an academic researcher from Montreal Heart Institute. The author has contributed to research in topics: Atrial fibrillation & Heart failure. The author has an hindex of 132, co-authored 778 publications receiving 65700 citations. Previous affiliations of Stanley Nattel include Mayo Clinic & Brigham and Women's Hospital.

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Journal Article

Autonomic modulation of the frequency-dependent actions of diltiazem on the atrioventricular node in anesthetized dogs.

TL;DR: In this article, the effects of four steady-state drug concentrations in each of seven dogs with intact autonomic tone, six with muscarinic blockade (atropine), and eight with combined musCAR and beta adrenergic blockade were evaluated.
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The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity.

TL;DR: A significant mechanism for defective choroidal revascularization in OIR is uncovered, revealing a new role for p53/let-7b/IGF-1R axis in the retina, and future investigations on this (and connected) pathway could further the understanding of other degenerative choroidopathies, such as geographic atrophy.
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A quantitative analysis of use-dependent ventricular conduction slowing by procainamide in anesthetized dogs.

TL;DR: Use-dependent conduction changes produced by procainamide in vivo closely follow the predictions of mathematical models of drug-channel interactions, and underlying kinetic interactions with the sodium channel inferred from conductionChanges agree with previous, more direct observations.
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Combined parasympathetic-sympathetic nerve discharge and pulmonary vein afterdepolarizations: a new unifying concept with basic and clinical relevance.

TL;DR: Data is presented that point to potentially important interacions between atrial autonomic nerves and the PVs in arhythmogenesis, and it is demonstrated that stimulation of PV reparations with rapid, very brief, and subthreshold stimulation cause rapid firing within PV sleeves.
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WITHDRAWN: 2017 HRS/EHRA/ECAS/APHRS/SOLAECE Expert Consensus Statement on Catheter and Surgical Ablation of Atrial Fibrillation

Hugh Calkins, +59 more