Stephen R. Quake

TL;DR: A variety of approaches to single-cell genomic analysis are discussed, highlighting the importance of understanding the behavior and heterogeneity of the individual cells that constitute the system and their interactions.

TL;DR: A microfluidic rectifier is presented: a microscopic channel of a special shape whose flow resistance is strongly anisotropic, differing by up to a factor of 2 for opposite flow directions.

TL;DR: This study demonstrates the clearance of latent Epstein–Barr virus genomes in a subpopulation of Burkitt’s lymphoma patient-derived cells with clustered regularly interspaced short palindromic repeat/Cas9 nuclease.

TL;DR: Deep single-cell RNA sequencing of microglia and related myeloid cells sorted from various regions of embryonic, postnatal, and adult mouse brains found that the majority of adult microglian signatures are remarkably similar in transcriptomes, regardless of brain region.

TL;DR: In this article, a microfluidic device consisting of pumps, valves, and fluid oscillation dampers is employed for sorting, where an entity is flowed by the pump along a flow channel through a detection region to a junction, and a waste or collection valve located on opposite branches of the flow channel at the junction are actuated, thereby routing the entity to either a waste pool or a collection pool.