S
Stephen R. Quake
Researcher at Stanford University
Publications - 626
Citations - 89247
Stephen R. Quake is an academic researcher from Stanford University. The author has contributed to research in topics: Transcriptome & Biology. The author has an hindex of 132, co-authored 589 publications receiving 77778 citations. Previous affiliations of Stephen R. Quake include Agency for Science, Technology and Research & Allegheny Health Network.
Papers
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Posted ContentDOI
Classifying Drosophila Olfactory Projection Neuron Subtypes by Single-cell RNA Sequencing
Hongjie Li,Felix Horns,Bing Wu,Qijing Xie,Jiefu Li,Tongchao Li,David J. Luginbuhl,Stephen R. Quake,Liqun Luo +8 more
TL;DR: It is shown that PNs use highly redundant combinatorial molecular codes to distinguish subtypes, enabling robust specification of cell identity and circuit assembly, and a new lineage-specific transcription factor is found that instructs PN dendrite targeting.
Patent
Surface chemistry and deposition techniques
TL;DR: In this article, surface chemistries for the visualization of labeled single molecules (analytes) with improved signal-to-noise properties are provided, where analyte molecules are bound to surface attachment features that are spaced apart on the surface.
Proceedings ArticleDOI
Spectrographic Microfluidic Memory
David Erickson,Baiyang Li,James R. Adleman,Saurabh Vyawahare,Stephen R. Quake,Demetri Psaltis +5 more
TL;DR: In this paper, a spectrographic optofluidic memory is proposed based on photoluminescent nanoparticles at discrete intensity levels which are suspended in liquids and mixed, delivered and stored using a series of soft and hard-lithography microfluidic structures.
Proceedings ArticleDOI
On-chip absorption and fluorescence spectroscopy with polydimethylsiloxane (PDMS) microfluidic flow channels
TL;DR: In this article, the authors describe a system which integrates PDMS microfluidic flow channels, a CMOS active pixel sensor (APS) imager, and commercial light sources for performing visible absorption and fluorescence spectroscopy.
Posted ContentDOI
Molecular and genetic regulation of pig pancreatic islet cell development
Seokho Kim,Robert L. Whitener,Heshan Peiris,Xueying Gu,Charles A. Chang,Jonathan Y. Lam,Joan Camunas-Soler,Insung Park,Romina J. Bevacqua,Krissie Tellez,Stephen R. Quake,Jonathan R. T. Lakey,Rita Bottino,Pablo J. Ross,Seung K. Kim +14 more
TL;DR: The findings, conceptual advances, and resources detailed here show how pig pancreatic islet studies complement or surpass other systems for understanding the developmental programs that generate functional β- and α-cells, and that are relevant to human diseases like diabetes mellitus.