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Timothy J. Craig
Researcher at Pennsylvania State University
Publications - 493
Citations - 21287
Timothy J. Craig is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Hereditary angioedema & Asthma. The author has an hindex of 69, co-authored 458 publications receiving 18340 citations. Previous affiliations of Timothy J. Craig include University of Bristol & San Diego State University.
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Journal ArticleDOI
Impact of Race on Asthma Treatment Failures in the Asthma Clinical Research Network
Michael E. Wechsler,Mario Castro,Erik Lehman,Vernon M. Chinchilli,E. Rand Sutherland,Loren C. Denlinger,Stephen C. Lazarus,Stephen P. Peters,Elliot Israel,Richard J. Martin,Stanley J. Szefler,Reuben M. Cherniack,Robert F. Lemanske,Christine A. Sorkness,Nizar N. Jarjour,Timothy J. Craig,Susan J. Kunselman,Homer A. Boushey,John V. Fahy,Monica Kraft,Steven A. Wasserman,Joe W. Ramsdell,William J. Calhoun,Bill T. Ameredes,Michael J. Walter,Eugene R. Bleecker,Emily DiMango,Gene R. Pesola,Robert Smith +28 more
TL;DR: Despite having fewer asthma symptoms and less rescue β-agonist use, African-Americans with asthma have more treatment failures compared with whites, especially when taking long-acting β-agonists.
Journal ArticleDOI
Homeostatic synaptic scaling is regulated by protein SUMOylation
Timothy J. Craig,Nadia Jaafari,Milos M. Petrovic,Milos M. Petrovic,Susan C. Jacobs,Philip Rubin,Jack R. Mellor,Jeremy M. Henley +7 more
TL;DR: Protein SUMOylation plays an important and previously unsuspected role in synaptic trafficking of AMPARs that underlies homeostatic scaling, and is identified as a SUMO substrate involved in the tetrodotoxin-induced increase in AMPAR surface expression.
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How ATP Inhibits the Open KATP Channel
TL;DR: It is shown that the ATP-dependent decrease in the mean burst duration is well described by a Monod-Wyman-Changeux model in which channel closing is produced by all four subunits acting in a single concerted step.
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Accumulated Dose in Liver Stereotactic-Body Radiotherapy: Positioning, Breathing and Deformation Effects
Michael Velec,Joanne Moseley,Timothy J. Craig,Timothy J. Craig,Laura A. Dawson,Laura A. Dawson,Kristy K. Brock,Kristy K. Brock +7 more
TL;DR: Investigating the accumulated dose deviations to tumors and normal tissues in liver stereotactic body radiotherapy (SBRT) and investigating their geometric causes concluded that accumulated SBRT dose may be warranted to pursue further dose escalation, adaptive S BRT, and aid in correlation with clinical outcomes.
Journal ArticleDOI
Canadian hereditary angioedema guideline
Stephen Betschel,Jacquie Badiou,Karen Binkley,Jacques Hébert,Amin Kanani,Paul K. Keith,Gina Lacuesta,Bill Yang,Emel Aygören-Pürsün,Jonathan A. Bernstein,Konrad Bork,Teresa Caballero,Marco Cicardi,Timothy J. Craig,Henriette Farkas,Hilary Longhurst,Bruce L. Zuraw,Henrik Balle Boysen,Rozita Borici-Mazi,Tom Bowen,Karen Dallas,John M. Dean,Kelly Lang-Robertson,Benoit Laramée,Eric Leith,Sean R. Mace,Christine McCusker,Bill Moote,Man-Chiu Poon,Bruce Ritchie,Donald Stark,Gordon Sussman,Susan Waserman +32 more
TL;DR: This guideline is intended to provide graded recommendations for the management of patients in Canada with HAE, including the treatment of attacks, short-term prophylaxis, long-termProphylactic, and recommendations for self-administration, individualized therapy, quality of life, and comprehensive care.