Michael J. Walter

TL;DR: When added to an inhaled glucocorticoid, tiotropium improved symptoms and lung function in patients with inadequately controlled asthma and its effects appeared to be equivalent to those with the addition of salmeterol.

TL;DR: Differences in receptor and cell-specific expression in these species suggest that differentiated human airway epithelial cell cultures may be superior for evaluation of some human strains, while the mouse can provide a model for studying avian strains that preferentially bind only the α2,3-linked SA receptor.

TL;DR: Primary graft dysfunction is associated with an increased risk of bronchiolitis obliterans syndrome independent of acute rejection, lymphocytic bronchitis, and community-acquired respiratory viral infections, and this risk is directly related to the severity of primary graft dysfunction.

TL;DR: It is shown that mice lacking the chemokine Ccl5 are immune compromised to the point of delayed viral clearance, excessive airway inflammation and respiratory death after mouse parainfluenza or human influenza virus infection.

TL;DR: It is shown that the IL-23-Th17 pathway regulates theIL-12-Th1 cell pathway and was required for protective immunity against F.tularensis live vaccine strain and a biological function for IL-17A in regulating IL- 12-Th 1 cell immunity and host responses to an intracellular pathogen.