Showing papers by "An-Najah National University published in 2016"

The global burden of injury: incidence, mortality, disability-adjusted life years and time trends from the Global Burden of Disease study 2013

Abstract: Background The Global Burden of Diseases (GBD), Injuries, and Risk Factors study used the disability-adjusted life year (DALY) to quantify the burden of diseases, injuries, and risk factors. This paper provides an overview of injury estimates from the 2013 update of GBD, with detailed information on incidence, mortality, DALYs and rates of change from 1990 to 2013 for 26 causes of injury, globally, by region and by country. Methods Injury mortality was estimated using the extensive GBD mortality database, corrections for ill-defined cause of death and the cause of death ensemble modelling tool. Morbidity estimation was based on inpatient and outpatient data sets, 26 cause-of-injury and 47 nature-of-injury categories, and seven follow-up studies with patient-reported long-term outcome measures. Results In 2013, 973 million (uncertainty interval (UI) 942 to 993) people sustained injuries that warranted some type of healthcare and 4.8 million (UI 4.5 to 5.1) people died from injuries. Between 1990 and 2013 the global age-standardised injury DALY rate decreased by 31% (UI 26% to 35%). The rate of decline in DALY rates was significant for 22 cause-of-injury categories, including all the major injuries. Conclusions Injuries continue to be an important cause of morbidity and mortality in the developed and developing world. The decline in rates for almost all injuries is so prominent that it warrants a general statement that the world is becoming a safer place to live in. However, the patterns vary widely by cause, age, sex, region and time and there are still large improvements that need to be made.

Global and national burden of diseases and injuries among children and adolescents between 1990 and 2013: findings from the global burden of disease 2013 study.

Abstract: Importance The literature focuses on mortality among children younger than 5 years. Comparable information on nonfatal health outcomes among these children and the fatal and nonfatal burden of diseases and injuries among older children and adolescents is scarce. Objective To determine levels and trends in the fatal and nonfatal burden of diseases and injuries among younger children (aged Evidence Review Data from vital registration, verbal autopsy studies, maternal and child death surveillance, and other sources covering 14 244 site-years (ie, years of cause of death data by geography) from 1980 through 2013 were used to estimate cause-specific mortality. Data from 35 620 epidemiological sources were used to estimate the prevalence of the diseases and sequelae in the GBD 2013 study. Cause-specific mortality for most causes was estimated using the Cause of Death Ensemble Model strategy. For some infectious diseases (eg, HIV infection/AIDS, measles, hepatitis B) where the disease process is complex or the cause of death data were insufficient or unavailable, we used natural history models. For most nonfatal health outcomes, DisMod-MR 2.0, a Bayesian metaregression tool, was used to meta-analyze the epidemiological data to generate prevalence estimates. Findings Of the 7.7 (95% uncertainty interval [UI], 7.4-8.1) million deaths among children and adolescents globally in 2013, 6.28 million occurred among younger children, 0.48 million among older children, and 0.97 million among adolescents. In 2013, the leading causes of death were lower respiratory tract infections among younger children (905 059 deaths; 95% UI, 810 304-998 125), diarrheal diseases among older children (38 325 deaths; 95% UI, 30 365-47 678), and road injuries among adolescents (115 186 deaths; 95% UI, 105 185-124 870). Iron deficiency anemia was the leading cause of years lived with disability among children and adolescents, affecting 619 (95% UI, 618-621) million in 2013. Large between-country variations exist in mortality from leading causes among children and adolescents. Countries with rapid declines in all-cause mortality between 1990 and 2013 also experienced large declines in most leading causes of death, whereas countries with the slowest declines had stagnant or increasing trends in the leading causes of death. In 2013, Nigeria had a 12% global share of deaths from lower respiratory tract infections and a 38% global share of deaths from malaria. India had 33% of the world’s deaths from neonatal encephalopathy. Half of the world’s diarrheal deaths among children and adolescents occurred in just 5 countries: India, Democratic Republic of the Congo, Pakistan, Nigeria, and Ethiopia. Conclusions and Relevance Understanding the levels and trends of the leading causes of death and disability among children and adolescents is critical to guide investment and inform policies. Monitoring these trends over time is also key to understanding where interventions are having an impact. Proven interventions exist to prevent or treat the leading causes of unnecessary death and disability among children and adolescents. The findings presented here show that these are underused and give guidance to policy makers in countries where more attention is needed.

A framework for water loss management in developing countries under fuzzy environment

Abstract: A multi-criteria decision analysis method for water loss management is proposed.The method integrates AHP and TOPSIS methods under fuzzy environment.It is applied to a real water distribution system in a developing country.The prevalent strategies were highly connected to the local conditions. Facing water scarcity conditions water utilities cannot longer tolerate inefficiencies in their water systems. To guarantee sustainable water management one central task is reducing water losses from the supply systems. There are numerous challenges in managing water losses, manifested in a variety of options, their complexities, multiple evaluation criteria, inherent uncertainties and the conflicting objectives and interests of different stakeholders. This study demonstrates the effectiveness of multi criteria decision analysis (MCDA) approaches for decision support in this complex topic. The study covers identifying the key options among a set of options that have been proposed within a framework of strategies to reduce water losses in water distribution systems of developing countries. The proposed methodology was initiated by developing a hierarchical structure of the decision problem that consists of four levels: Overall objective, main criteria, evaluation criteria and options. Different stakeholders were engaged in the process of structuring and evaluating the decision problem. An integrated methodology that combines fuzzy set theory with Analytic Hierarchy Process (AHP) and Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) methods was then employed. This methodology has the potential to transform qualitative data into equivalent quantitative measures. Fuzzy AHP was used to create weights for main and evaluation criteria, while Fuzzy TOPSIS was used to aid the ranking of options in terms of their potential to meet the overall objective based on the evaluations and preferences of decision makers. The results showed that pressure management and control strategy was the most prevalent one, followed by employing advanced techniques and establishment of district metered areas. Their dominance was highly connected to the local and boundary conditions of the case study. The sensitivity analysis results showed that strongest and weakest options were less sensitive to changes in weights of evaluation criteria, which could be attributed to the strong consensus in strengthening the best option and neglecting the worst option. This study emphasized the successful application of MCDA in dealing with complicated issues in the context of water loss management. It is anticipated that, the integration of this developed framework in the planning policies of water utilities in developing countries can help in conducting better control over water losses.

Suicidal Behavior and Psychological Distress in University Students: A 12-nation Study.

Abstract: This study investigated the prevalence of suicidal behavior and psychological distress in university students across 12 nations. A total of 5,572 university students from 12 countries were surveyed about suicide ideation, suicide attempts, and psychological distress by means of a self-administered questionnaire. Almost 29% of the samples reported having contemplated suicide and 7% reported attempting suicide. Of the total sample, 51.1% scored above the General Health Questionnaire-12 ≥ 3 cut-off points, 41.6% above the GHQ-12 ≥ 4 cut-off points, and 33.8% scored above the GHQ-12 ≥ 5 cut-off points. While odds of suicide ideation were elevated in Austria and the UK, reduced ORs were detected for China, Italy, Saudi Arabia, Tunisia, and Turkey. Similarly, while odds of suicide attempt were high in Jordan, Palestine, Saudi Arabia, and to some extent in Turkey, reduced ORs were observed for Austria, China, Italy, Japan and the United States. Elevated ORs for psychological distress were seen in Japan, Jordan, ...

Global research trends of Middle East respiratory syndrome coronavirus: a bibliometric analysis

Abstract: Middle East respiratory syndrome coronavirus (MERS-CoV) is a virus that causes severe viral pneumonia in humans, known to have a high mortality rate and a similarity in clinical symptoms with severe acute respiratory syndrome coronavirus. It was first isolated in Kingdom of Saudi Arabia (KSA) in 2012 and after that, MERS-CoV exhibited outbreaks in several regions of the world. This study aimed to assess the characteristics of publications involving MERS-CoV at global level by using a bibliometric analysis. Scopus database was searched on March 4, 2016 for MERS-CoV publications published between 2012 and 2015. It was performed on the same day in order to avoid the possible bias came from update on the database because the metrics are changing over time. All publication types were considered; however publications as errata were excluded. Analysis parameters include year of publication, publication type, patterns of international collaboration, research institutions, journals, impact factor, h-index, language, and times cited. A total of 883 MERS-CoV research publications were published across the world. The MERS-CoV-associated publications were originated from 92 countries/territories, indicating the international spread of MERS-CoV research. The USA was the largest contributor, with 319 articles published over 4 years, followed by KSA (113 articles). The total number of citations for these publications has already achieved 8,015, with an average of 9.01 citations per each publication. The h-index for MERS-CoV-associated publications was 48. The USA also have the highest h-index (32), followed by KSA (26) and UK (22). Netherland produced the greatest proportion of publications with international research collaboration (72.7 %) followed by the UK (71 %) and Germany (69.1 %) out of the total number of publications for each country. There is a rapid increase in research activities related to MERS-CoV from 2012 to 2015. This study demonstrates that the MERS-CoV related literature has grown to be more extensive and global over the past 4 years. The bulk of publications in the field of MERS-CoV research are published by high-income countries such as the USA. Furthermore, the USA, the UK and KSA may have higher quality of articles according to the value of h-index.

Factors affecting quality of life in patients on haemodialysis: a cross-sectional study from Palestine

Abstract: Haemodialysis (HD) is a life-sustaining treatment for patients with end-stage renal disease (ESRD). HD can bring about significant impairment in health-related quality of life (HRQOL) and outcomes. Therefore, we sought to describe the patterns of HRQOL and determine the independent factors associated with poor HRQOL in Palestinian patients on HD. A multicenter cross-sectional study was performed from June 2014 to January 2015 using the EuroQOL-5 Dimensions instrument (EQ-5D-5L) for the assessment of HRQOL. ESRD patients undergoing HD in all dialysis centres in the West Bank of Palestine were approached and recruited for this study. Multiple linear regression was carried out to identify factors that were significantly associated with HRQOL. Two hundred and sixty-seven patients were participated in the current study giving response rate of 96 %. Overall, 139 (52.1 %) were male, and the mean ± standard deviation age was 53.3 ± 16.2 years. The reported HRQOL as measured by mean EQ-5D-5L index value and Euro QOL visual analogue scale (EQ-VAS) score was 0.37 ± 0.44 and 59.38 ± 45.39, respectively. There was a moderate positive correlation between the EQ-VAS and the EQ-5D-5L index value (r = 0.42, p < 0.001). The results of multiple linear regression showed a significant negative association between HRQOL with age, total number of chronic co-morbid diseases and the total number of chronic medications. However, a significant positive association was found between HRQOL with male gender, university education level and patients who live in village. Our results provided insight into a number of associations between patient variables and their HRQOL. Healthcare providers should be aware of low HRQOL among patients with no formal education, female gender, patient’s residents of refugee camps, multiple co-morbid diseases, multiple chronic medications, and elderly patients to improve their quality of life.

Smart real-time healthcare monitoring and tracking system using GSM/GPS technologies

Abstract: Health monitoring systems have rapidly evolved recently, and smart systems have been proposed to monitor patient current health conditions, in our proposed and implemented system, we focus on monitoring the patient's blood pressure, and his body temperature. Based on last decade statistics of medical records, death rates due to hypertensive heart disease, shows that the blood pressure is a crucial risk factor for atherosclerosis and ischemic heart diseases; thus, preventive measures should be taken against high blood pressure which provide the ability to track, trace and save patient's life at appropriate time is an essential need for mankind. Nowadays, Globalization demands Smart cities, which involves many attributes and services, such as government services, Intelligent Transportation Systems (ITS), energy, health care, water and waste. This paper proposes a system architecture for smart healthcare based on GSM and GPS technologies. The objective of this work is providing an effective application for Real Time Health Monitoring and Tracking. The system will track, trace, monitor patients and facilitate taking care of their health; so efficient medical services could be provided at appropriate time. By Using specific sensors, the data will be captured and compared with a configurable threshold via microcontroller which is defined by a specialized doctor who follows the patient; in any case of emergency a short message service (SMS) will be sent to the Doctor's mobile number along with the measured values through GSM module. furthermore, the GPS provides the position information of the monitored person who is under surveillance all the time. Moreover, the paper demonstrates the feasibility of realizing a complete end-to-end smart health system responding to the real health system design requirements by taking in consideration wider vital human health parameters such as respiration rate, nerves signs … etc. The system will be able to bridge the gap between patients — in dramatic health change occasions- and health entities who response and take actions in real time fashion.

An overview of renewable energy potential in Palestine

Abstract: The energy sector situation in Palestine is highly different compared to other countries in the Middle East due to many reasons: non-availability of natural resources, unstable political conditions, financial crisis and high density population. Furthermore, Palestine depends on other countries for 100% of its fossil fuel imports and for 87% of its electricity imports. In addition high growth of population, increasing living standards and rapid growth of industrial have led to tremendous energy demand in Palestine in recent years. The total energy consumption per habitant in Palestine is the lowest in the region (0.79 MW h/inhabitant) and costs more than anywhere else in the Middle East countries. The primary goal of this paper is to analyze the current energy sector situation in Palestine and to highlight the status of the potential of renewable energy as an essential future energy source sector in Palestine. Regarding the main possibilities of RE, the wind speed averages (m/s) for main 5 cities were: Tubas 4.97, Salfeet 4.26, Ramallah 3.09, Hebron 2.90 and Jericho 1.32. With these data, Palestine can be considered as a country of moderate wind speeds. By the other hand, Palestine has a high solar energy potential about 3000 sunshine hours per year with a solar radiation (kW h/m2/day) for year 2013 of 8.27 in Ramallah, 7.51 in Hebron, 6.86 in Salfeet and 6.15 in Tubas. These values are encouraging to exploit the solar energy for different applications. This study highlights that the main renewable energy sources in Palestine are solar energy, wind energy and biomass, thereby the energy dependence on neighbouring countries may significantly decrease, when Palestine uses the available renewable energy sources. The renewable energies in Palestine open new perspectives for energy sector in order to prompt practices for sustainable development.

Search for squarks and gluinos in events with an isolated lepton, jets, and missing transverse momentum at s=13 TeV with the ATLAS detector

Abstract: The results of a search for gluinos in final states with an isolated electron or muon, multiple jets and large missing transverse momentum using proton--proton collision data at a centre-of-mass energy of $\sqrt{s}$ = 13 TeV are presented. The dataset used was recorded in 2015 by the ATLAS experiment at the Large Hadron Collider and corresponds to an integrated luminosity of 3.2 fb$^{-1}$. Six signal selections are defined that best exploit the signal characteristics. The data agree with the Standard Model background expectation in all six signal selections, and the largest deviation is a 2.1 standard deviation excess. The results are interpreted in a simplified model where pair-produced gluinos decay via the lightest chargino to the lightest neutralino. In this model, gluinos are excluded up to masses of approximately 1.6 TeV depending on the mass spectrum of the simplified model, thus surpassing the limits of previous searches.

Bibliometric analysis of worldwide publications on multi-, extensively, and totally drug – resistant tuberculosis (2006–2015)

Abstract: The year 2015 marked the end of United Nations Millennium Development Goals which was aimed at halting and reversing worldwide tuberculosis (TB). The emergence of drug resistance is a major challenge for worldwide TB control. The aim of this study was to give a bibliometric overview of publications on multi-, extensively, and totally drug-resistant TB. Scopus database was used to retrieve articles on multidrug resistant (MDR), extensively drug-resistant (XDR), and totally drug-resistant (TDR) tuberculosis for the study period (2006–2015). The number of publications, top productive countries and institutions, citation analysis, co-authorships, international collaboration, active authors, and active journals were retrieved and analyzed. A total of 2260 journal articles were retrieved. The mean ± SD citations per article was 7.04 ± 16.0. The h-index of retrieved data was 76. The number of publications showed a three – fold increase over the study period compared with less than two – fold increase in tuberculosis research during the same study period. Stratified by number of publications, the United States of America ranked first while Switzerland ranked first in productivity per 100 million people, and South Africa ranked first in productivity stratified per one trillion Gross Domestic Product. Three of the High Burden Countries (HBC) MDR-TB (India, China, and South Africa) were present in top productive countries. High percentage of international collaboration was seen among most HBC MDR-TB. Except for Plos One journal, most active journals in publishing articles on MDR, XDR, TDR-TB were in infection – related fields and in general medicine. Top 20 cited articles were published in prestigious journal such as Lancet and New England Journal of Medicine. The themes in top 20 cited articles were diverse, ranging from molecular biology, diagnostic tools, co-infection with HIV, and results of new anti-TB drugs. Publications on MDR, XDR and TDR – TB are increasing in the past decade. International collaboration was common. Many low resourced African and Asian countries will benefit from research leading to new diagnostic and screening technology of TB. The exchange of expertise, ideas and technology is of paramount importance in this field.

Bibliometric analysis of publications on Campylobacter : (2000–2015)

Abstract: Campylobacter species are widespread zoonotic pathogens. Campylobacter jejuni causes a form of gastroenteritis called campylobacteriosis. Campylobacter drug resistance is considered a serious threat. In order to better understand national and international research output on Campylobacter, we conducted this bibliometric overview of publications on Campylobacter. This study can be used to assess extent of interaction and response of researchers, food regulators, and health policy makers to global burden of campylobacateriosis. Scopus database was used to retrieve publications with the following keywords (Campylobacter/campylobacteriosis, C. jejuni, C. coli). The study period was set from 2000 to 2015. All types of journal documents, excluding errata, were considered. Bibliometric indicators such as annual growth of publications, country contribution, international collaboration, and citation analysis were presented. The quality of retrieved data was indirectly assessed by Hirsch index and impact factor of journals. A total of 5522 documents were retrieved with median (Q1–Q3) citations of 9 (2–23) and h-index of 113. Annual number of publications showed a fluctuating increase. The core leading journals were Applied and Environmental Microbiology journal and Journal of Food Protection with 246 (4.46%) publications for each. The USA (1309; 23.6%) was the most productive country while Danmarks Tekniske Universitet (150; 2.7%) was the most productive institution. Half of the top ten productive countries were European. France had the lowest percentage (33.5%) of articles with international collaboration while Netherlands (57.7%) had the highest percentage of articles with international collaboration. Approximately half (50.1%) of retrieved articles were published in journals under the subject area of “immunology/microbiology”. Main themes in highly cited articles were molecular biology/genetics and public health burden of campylobacteriosis. There were 728 (13.1%) articles on campylobacter-related drug resistance, and the top cited articles focused mainly on increasing resistance to quinolones and fluoroquinolones. There was a clear increase in number of publications on Campylobacter. Rational use of antimicrobials in humans, poultry, and animals is highly recommended. International collaboration is highly required particularly in implementing new diagnostic screening technologies to minimize global health burden of Campylobacter and ensure food safety.

Ethnopharmacological survey of herbal remedies used for treatment of various types of cancer and their methods of preparations in the West Bank-Palestine.

Abstract: Plants have been the primary source of medicines since life on earth; more than 50 % of existing cancer treatments are derived from plants. An ethnopharmacological survey of herbal remedies used in cancer treatment was carried out in the West Bank/ Palestine. A questionnaire was distributed to one hundred and fifty herbalists, traditional healers and rural dwellers. Collected information included the names of plants, the used parts, types of cancers for which these plants were used and also their methods of preparation. To identify the most important species used, Factor of informant’s consensus (Fic), Fidelity level (Fl) and the Use-value (UV) were calculated. Collected data has shown that 72 plants are utilized for treatment of cancer, belonging to 44 families; from them Compositae and Lamiaceae were the most common. Leaves and fruits were the most commonly used parts, while decoctions, infusions and syrups were the main methods of preparation. Lung cancer was the most common type of cancer treated with these plants and Ephedra alata was the most commonly used plant for treatment of cancer in Palestine. The Fic was high for all the plants; Fl was 100 % for many plants, the highest UV (0.72) was for Ephedra alata. This study showed that many herbal remedies are still used by herbalists in Palestine for treatment of cancer; some of them have been approved scientifically while others are not. A combined effort between informants and scientific institutions working in this field can help in the discovery of new anticancer agents. Moreover, scientists must explore the most suitable method of extraction, formulation and dose determination in order to achieve the best benefits from these herbals.

Anticancer Activity, Antioxidant Activity, and Phenolic and Flavonoids Content of Wild Tragopogon porrifolius Plant Extracts

Abstract: Tragopogon porrifolius, commonly referred to as white salsify, is an edible herb used in folk medicine to treat cancer. Samples of Tragopogon porrifolius plant grown wild in Palestine were extracted with different solvents: water, 80% ethanol, and 100% ethanol. The extracts were analyzed for their total phenolic content (TPC), total flavonoid content (TFC), and antioxidant activity (AA). Four different antioxidant assays were used to evaluate AA of the extracts: two measures the reducing power of the extracts (ferric reducing antioxidant power (FRAP) and cupric reducing antioxidant power (CUPRAC)), while two other assays measure the scavenging ability of the extracts (2,2-azino-di-(3-ethylbenzothialozine-sulphonic acid (ABTS)) and 2,2-diphenyl-1-picrylhydrazyl (DPPH)). Anticancer activity of the plant extracts were also tested on HOS and KHOS osteosarcoma cell lines. The results revealed that the polarity of the extraction solvent affects the TPC, TFC, and AA. It was found that both TPC and AA are highest for plant extracted with 80% ethanol, followed by water, and finally with 100% ethanol. TFC however was the highest in the following order: 80% ethanol > 100% ethanol > water. The plant extracts showed anticancer activities against KHOS cancer cell lines; they reduced total cell count and induced cell death in a drastic manner.

An overview of energy balance compared to sustainable energy in United Arab Emirates

Abstract: This paper summarized an overview of energy balance and greenhouse gas emissions at UAE in order to prompt renewable and sustainable energy practices. Electricity demand has been increasing dramatically in the United Arab Emirates (UAE) in the last decade. Electricity production increased 5.39 TWh each year from 2000 (39.9 TWh) to 2013 (110 TWh), which means an annual increase of more than 13.5%. The electric power consumption has increased 5.14 TWh each year in the same period; which is 13.3% each year. The electricity consumption per capita is an indicator that places UAE in the group of highest consumption countries worldwide; namely, UAE ranks 10th in 2012 with 10.13 MWh per capita. UAE׳s population and economic growth are the main causes of a sharp increase in energy demand. On the other hand, UAE ranked 25th worldwide for CO2 emissions. However, UAE is not in the top pollutant countries in the world with respect to CO2 emissions per capita. More specifically, UAE has dropped from the 2nd position in the period 2000–2004 to 8th in 2010 and in year 2013 occupied again 2nd position among the global most pollutant countries. On the other hand, UAE has huge amount of available solar resources; the active and passive use of solar energy could be an approach to reduce even more the fossil energy consumption and the greenhouse gas emissions. It is essential to define the future role of the different sources of energy and to outline the required steps to move into a sustainable future energy system. These may achieve environmentally sustainable power development.

Dengue research: a bibliometric analysis of worldwide and Arab publications during 1872-2015.

Abstract: Dengue is an important emerging and re-emerging arboviral infection globally as a rapidly growing and widespread public health problem, with transmission occurring in more than 128 countries in Asia, Americas, southeast Africa, western Pacific, and eastern Mediterranean regions. Therefore, the aim of this study was to characterize and quantify the scientific output of dengue research in Arab countries relative to that worldwide by using a bibliometric analysis. The standardized search approach based on the use of the the keyword “dengue” in the title, abstract, and keyword field was used to get research output related to dengue at a global level. All data related to dengue were collected from the past to December 31, 2015. A total of 19,581 dengue-related documents identified in the Scopus database. The results show that the study of dengue exhibits an overall upward trend from 1872 to 2015 with peak publications in 2014. The leading countries in dengue research were the USA (4,709; 24.05 %), India (1,942; 9.92 %), Brazil (1,530; 7.81 %), Thailand (1,260; 6.43 %), the UK (1,129; 5.77 %), and France (1,087; 5.55 %). Only 226 (1.16 % of the overall global research effort in the dengue field) articles were published from the Arab region. The total number of citations for all publications was 352,710, with an average of 18.0 citations per publication. Furthermore, the h-index for all extracted data related to dengue research was 186. Kingdom of Saudi Arabia (KSA) was the most productive country in Arab region with 102 documents representing 45.1 %. Furthermore, the h-index for all extracted data related to dengue research was 27. The USA was Arab’s most main cooperative partner (46, 20.4 %), followed by India (36, 15.9 %). The amount of literature related to dengue research has considerably increased over the last decade. This bibliometric analysis has demonstrated the leading role that the USA, India, Brazil, Thailand, the UK, and France play in dengue research. The Arab world produced fewer publications related to dengue with lower quality than other world countries.

Bibliometric profile of the global scientific research on autism spectrum disorders

Abstract: Autism spectrum disorders (ASD) are a group conditions classified as neuro-developmental disorders. Research activity on ASD is important for all countries since such disorders have both social and health consequences. The objective of this study was to analyze research output on ASD during the period 2005–2014. All articles relevant to ASD plus all articles published in autism journals were retrieved using Scopus database. VOSviewer software was used to create density and network visualization maps. Bibliometric indicators were investigated by analyzing annual research output, languages, countries, institutions, journals, title terms, highly cited articles, and co-authorship relations. A progressive annual growth of ASD research was observed from 2005 to 2014. During this period, a total of 18,490 articles were retrieved. The majority of these articles was published in Journal of Autism and Developmental Disorders with 48,416 citations and an average citation of 23.59 citations per article. The countries that published the largest number of articles were the United States (US) (n = 8594; 46.48 %), United Kingdom (n = 2430; 13.14 %) and Canada (n = 1077; 5.8 %). International collaborations produced 30.18 % of the articles published by top 10 productive countries. King’s College London (UK) ranked first in number of publications and total citations. The top 10 list of productive institutions was dominated by US academic and research institutions. More than half of the highly cited articles were in the field of molecular genetics. Articles with more than 50 citations were published mainly by authors from USA, UK and Canada. There is a worldwide growth of publications on ASD led by countries in Northern America and Europe. Retrieved articles were published in a wide range of journals. Molecular genetics of ASD is the primary hot topic on ASD. For some leading countries, intra country collaboration is dominant.

The effect of the nanosize on surface properties of NiO nanoparticles for the adsorption of Quinolin-65

Abstract: Using Quinolin-65 (Q-65) as a model-adsorbing compound for polar heavy hydrocarbons, the nanosize effect of NiO nanoparticles on the adsorption of Q-65 was investigated. Different-sized NiO nanoparticles with sizes between 5 and 80 nm were prepared by the controlled thermal dehydroxylation of Ni(OH)2. The properties of the nanoparticles were characterized using XRD, BET, FTIR, HRTEM and TGA. The effects of the nanosize on the textural properties, the shape and the morphology were studied. The adsorption of Q-65 molecules onto different-sized nanoparticles was tested in toluene-based solutions. On a normalized surface area basis, the number of Q-65 molecules adsorbed per nm(2) of the NiO surface was the highest for NiO nanoparticles of size 80 nm, while that for 5 nm sized NiO nanoparticles was the lowest. Excitingly, the adsorption capacity of other NiO sizes varied from loading suggesting different adsorption behavior, which exhibits the significance of textural properties during the adsorption of Q-65. Computational modeling of the interaction between the Q-65 molecule and the NiO nanoparticle surface was carried out to get more understanding of its adsorption behavior. A number of factors contributing to the enhanced adsorption capacity of nanoscale NiO were determined. These include surface reactivity, topology, morphology and textural properties.

Use of complementary and alternative medicines in haemodialysis patients: a cross-sectional study from Palestine

Abstract: Complementary and alternative medicine (CAM), and herbal therapies, are accepted worldwide, and have been important from medical, sociological and economic perspectives, among haemodialysis (HD) patients. The primary aim of this study was to evaluate the use of CAM among patients with end-stage renal disease (ESRD) who are undergoing HD. Face-to-face interviews of patients with ESRD undergoing HD from ten outpatient renal departments at a national level in Palestine were conducted from June 2014 to January 2015. A survey questionnaire, which included questions on socio-demographic and clinical characteristics, and on the CAM therapies that were used, was administered. Out of 267 patients interviewed, 172 patients used at least one type of CAM in the last month prior to the interview, and thus the utilisation rate was 64.4 %. Forty one (15.4 %) patients reported using one type of CAMs, while 18.7 % used two different CAMs and 30.3 % used more than two types of CAMs for their health status. Of the patients who used CAM, herbal therapies were used most often (43.5 %), followed by honey (35.6 %), diet (22.8 %), and exorcism in Islam (16.9 %). The herbal therapies mentioned most often were Nigella sativa L. (18.7 %), followed by Salvia officinalis L. (16.9 %), and Pimpinella anisum L. (10.5 %). In conclusion, the prevalence of CAM is relatively high in the selected population. Most patients used biological therapies such as herbal remedies, thus highlighting a greater need for patient education regarding CAM therapies and possible herb-drug interactions. Health care providers must be aware of the potential benefits and risks related to CAM use. There is a need for more clinical research pertaining to CAM to reach stronger evidence regarding potential benefits and risks related to CAM use.