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Institution

Boston University

EducationBoston, Massachusetts, United States
About: Boston University is a education organization based out in Boston, Massachusetts, United States. It is known for research contribution in the topics: Population & Poison control. The organization has 48688 authors who have published 119622 publications receiving 6276020 citations. The organization is also known as: BU & Boston U.


Papers
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Journal ArticleDOI
TL;DR: It is found that the successive increments in the cardiac beat-to-beat intervals of healthy subjects display scale-invariant, long-range anticorrelations (up to 10(4) heart beats), and the different scaling behavior in health and disease must relate to the underlying dynamics of the heartbeat.
Abstract: We find that the successive increments in the cardiac beat-to-beat intervals of healthy subjects display scale-invariant, long-range anticorrelations (up to 10 exp 4 heart beats). Furthermore, we find that the histogram for the heartbeat intervals increments is well described by a Levy (1991) stable distribution. For a group of subjects with severe heart disease, we find that the distribution is unchanged, but the long-range correlations vanish. Therefore, the different scaling behavior in health and disease must relate to the underlying dynamics of the heartbeat.

948 citations

Journal ArticleDOI
TL;DR: Although still unfamiliar to many health researchers, the use of false discovery rate control in the context of multiple testing can provide a solid basis for drawing conclusions about statistical significance.

947 citations

Journal ArticleDOI
TL;DR: The authors propose that PD develops because exposure to panic attacks causes the conditioning of anxiety (and sometimes panic) to exteroceptive and interoceptive cues, which begins the individual's spiral into PD.
Abstract: Several theories of the development of panic disorder (PD) with or without agoraphobia have emerged in the last 2 decades. Early theories that proposed a role for classical conditioning were criticized on several grounds. However, each criticism can be met and rejected when one considers current perspectives on conditioning and associative learning. The authors propose that PD develops because exposure to panic attacks causes the conditioning of anxiety (and sometimes panic) to exteroceptive and interoceptive cues. This process is reflected in a variety of cognitive and behavioral phenomena but fundamentally involves emotional learning that is best accounted for by conditioning principles. Anxiety, an anticipatory emotional state that functions to prepare the individual for the next panic, is different from panic, an emotional state designed to deal with a traumatic event that is already in progress. However, the presence of conditioned anxiety potentiates the next panic, which begins the individual's spiral into PD. Several biological and psychological factors create vulnerabilities by influencing the individual's susceptibility to conditioning. The relationship between the present view and other views, particularly those that emphasize the role of catastrophic misinterpretation of somatic sensations, is discussed.

947 citations

Journal ArticleDOI
TL;DR: An evidence-based review of plausible causal pathways that could best explain well-established associations between limited health literacy and health outcomes is provided.
Abstract: Objective To provide an evidence-based review of plausible causal pathways that could best explain well-established associations between limited health literacy and health outcomes. Methods Through analysis of current findings in medical and public health literature on health literacy we derived a conceptual causal model. Results Health literacy should be viewed as both a patient and a system phenomenon. Three distinct points along a continuum of health care are suggested to be influenced by health literacy: (1) access and utilization of health care, (2) patient-provider relationship, and (3) self-care. Conclusions The conceptual model organizes what has been learned to date and underscores promising areas of future inquiry and intervention.

947 citations

Journal ArticleDOI
TL;DR: An overview of the as-built instrument characteristics and the application of MISR to remote sensing of the Earth is provided.
Abstract: The Multi-angle Imaging SpectroRadiometer (MISR) instrument is scheduled for launch aboard the first of the Earth Observing System (EOS) spacecraft, EOS-AM1. MISR will provide global, radiometrically calibrated, georectified, and spatially coregistered imagery at nine discrete viewing angles and four visible/near-infrared spectral bands. Algorithms specifically developed to capitalize on this measurement strategy will be used to retrieve geophysical products for studies of clouds, aerosols, and surface radiation. This paper provides an overview of the as-built instrument characteristics and the application of MISR to remote sensing of the Earth.

947 citations


Authors

Showing all 49233 results

NameH-indexPapersCitations
Walter C. Willett3342399413322
Robert Langer2812324326306
Meir J. Stampfer2771414283776
Ronald C. Kessler2741332328983
JoAnn E. Manson2701819258509
Albert Hofman2672530321405
George M. Whitesides2401739269833
Paul M. Ridker2331242245097
Eugene Braunwald2301711264576
Ralph B. D'Agostino2261287229636
David J. Hunter2131836207050
Daniel Levy212933194778
Christopher J L Murray209754310329
Tamara B. Harris2011143163979
André G. Uitterlinden1991229156747
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Performance
Metrics
No. of papers from the Institution in previous years
YearPapers
2023223
2022810
20216,943
20206,837
20196,120
20185,593