Institut de veille sanitaire

About: Institut de veille sanitaire is a healthcare organization based out in Saint-Maurice, France. It is known for research contribution in the topics: Population & Public health. The organization has 1055 authors who have published 1547 publications receiving 56945 citations. The organization is also known as: INVS & InVS.

Compensation of pleural mesothelioma in France: data from the French National Mesothelioma Surveillance Programme.

Abstract: Background The aim of this study was to determine the rates of compensation awarded to patients presenting with pleural mesothelioma and factors linked to such compensation in France. Methods The study population consisted of 2,407 patients presenting with pleural mesothelioma, recorded by the National Mesothelioma Surveillance Programme between January 1, 1999 and December 31, 2009. Analysis of claims for recognition as “occupational disease” (OD) and claims for compensation by the Compensation Fund for Asbestos Victims (FIVA) were analyzed. Results Approximately 30% of subjects presenting with pleural mesothelioma, affiliated to the General National Health Insurance fund, neither sought recognition as an OD nor claimed for FIVA compensation. Gender, age at diagnosis, type of health insurance, and socio-professional category influence the likelihood of patients presenting with mesothelioma seeking compensation for this disease. Conclusions Results show an under-compensation of pleural mesothelioma as OD and by the FIVA in France. Am. J. Ind. Med. 56:146–154, 2013. © 2011 Wiley Periodicals, Inc.

La surveillance des maladies infectieuses : principes et organisation en France en 2005

Abstract: Resume La surveillance est le « processus continu et systematique de collecte, de compilation, et d'analyse de donnees de sante ainsi que leur diffusion a tous ceux qui ont contribue a la collecte et a tous ceux qui ont besoin d'etre informes pour agir ». En lien direct avec l'action et la decision, les actions de surveillance s'interessent en priorite a des problemes de sante pouvant faire l'objet d'un traitement, d'une prevention ou d'une action de sante publique. Les objectifs de la surveillance sont le suivi des tendances et des caracteristiques de la maladie consideree ; l'evaluation des politiques et strategies de controle et de prevention des maladies infectieuses et l'alerte par la detection precoce de l'emergence de nouvelles pathologies infectieuses et de la survenue de phenomenes epidemiques. Les informations ainsi generees permettent de prioriser les actions et de preciser voire definir les objectifs de controle et de prevention. La surveillance des maladies infectieuses repose sur de nombreux partenaires et intervenants qui forment un reseau national de sante publique au sein duquel les cliniciens et les biologistes sont en premiere ligne. Le dispositif de surveillance francais des maladies infectieuses est fonde sur la declaration obligatoire, les centres nationaux de reference, des reseaux de professionnels volontaires et des enquetes repetees. Ces systemes sont coordonnes par l'Institut de Veille Sanitaire qui a pour mission de surveiller l'etat de sante de la population, d'alerter les pouvoirs publics sur les menaces de sante publique, et d'etudier les determinants des modifications de tendances de l'etat de sante.

Une estimation des décès traumatiques liés à la pratique sportive en France métropolitaine, en 2010

Abstract: Resume Introduction L’exercice physique est benefique pour la sante, mais il peut aussi entrainer des accidents, plus ou moins graves, dont certains conduisent au deces. L’objectif de cette etude etait d’estimer le nombre de deces traumatiques lies a la pratique sportive en 2010, en France metropolitaine. Methode L’etude a consiste a recueillir les deces traumatiques survenus en 2010 en France metropolitaine a la suite d’une pratique sportive, quel que soit le contexte de pratique (professionnel, loisir, deplacement). Seuls ont ete exclus les deces a velo, les deces en avion et par noyade survenus hors pratique sportive. Les deces ont ete reperes dans des collectes d’institutions publiques, dans les medias accessibles par Internet et sur les sites Internet d’associations et d’organismes publics impliques dans le sport. Resultats En 2010, 246 personnes sont decedees suite a une pratique sportive en France metropolitaine. Les sports de montagne ont ete les plus meurtriers (99 deces) suivis des sports aquatiques (50), de la chasse (27), de la pratique aerienne (23 dont 22 ULM), des sports mecaniques (23) et des sports de vol libre (20 dont dix en parapente et cinq en planeur). Les hommes etaient sept fois plus nombreux que les femmes. Les periodes les plus meurtrieres etaient l’ete et l’hiver. Discussion Des cas ont echappe a cette comptabilisation, entrainant une sous-estimation dans certains sports (equitation, peche…) ou lorsque les deces n’ont pas ete immediats. Cette etude simple, qui doit etre completee, a fourni un premier decompte du nombre de deces traumatiques en sport en France metropolitaine.

Molecular epidemiology and clinical characteristics of hepatitis B identified through the French mandatory notification system.

Abstract: Background & Aims Strains responsible for acute hepatitis B infections (AHB) in France have not been characterized. This study was first designed to analyze the molecular epidemiology of AHB and second to describe the differences between AHB and chronic hepatitis B (CHB) exacerbations. Methods This prospective study was based on the French mandatory notification system for AHB. 147 samples corresponding to declared cases were shipped to a central laboratory for classification as AHB or CHB according to the level of anti-HBc IgM and anti-HBc avidity. Results Based on biological marker values and file examination, 75 cases (59%) were classified as AHB. Independently of the acute or chronic status, genotype A (57%), D (22%) and E (14%) were the most prevalent and no phylogenetic clustering was observed among HBV sequences (n=68). Precore or basal core-promoter variants were not particularly associated with disease severity but were more prevalent in CHB. No antiviral resistant strains or immune-escape HBsAg was observed. HBV viral loads in AHB or CHB were comparable but with opposite distributions. ALT levels reached 10 times the upper normal value in 94% of AHB but only in 24% of CHB. Conclusions After rigorous classification, no major difference at the genetic level was found between HBV strains isolated from AHB and CHB. Absence of potentially deleterious variant detection is reassuring. When based upon HBsAg and anti-HBc IgM determination, AHB notification may falsely include more than 40% CHB, leading to an important risk of bias in national surveillance programs of AHB.

Characterization of a French series of female cases of mesothelioma

Abstract: Background More than 80% of mesothelioma cases in men are attributable to occupational asbestos exposure compared to only 40% in women. The objective of the study was to characterize a series of female pleural mesotheliomas according to known and suspected risk factors. Methods From the exhaustive recording of 318 female mesothelioma cases in the French National Mesothelioma Surveillance Program between 1998 and 2009, multiple correspondence analysis and hybrid clustering were performed to characterize these cases according to expert assessed occupational and non-occupational exposure to asbestos and man-made vitreous fibers, X-ray exposure, and history of cancer and non-malignant respiratory diseases. Results Four clusters were identified: (1) occupational exposure to asbestos and man-made vitreous fibers (7.9% of subjects); (2) radiation exposure during radiotherapy (12.9%); (3) increased asbestos exposure (19.8%); and (4) “non-exposure” characteristics (59.4%). Conclusion These results will allow hypotheses to be generated about associations between mesothelioma and non-occupational asbestos exposure, X-ray exposure and history of respiratory disease. Am. J. Ind. Med. 56:1307–1316, 2013. © 2013 Wiley Periodicals, Inc.